Published in Cell Reports · View the paper (DOI)
Researchers discovered that older mice exhibit increased tissue regeneration and decreased scar formation in skin wounds. The findings were confirmed in human studies, suggesting that aging suppresses the circulating factor SDF1, which promotes scar formation. The study's authors hope to develop a drug to prevent scarring in humans.
Coverage from 2 institutions
- Skin wounds in older mice are less likely to scar Cell Press · Sep 25, 2018 · first to report
- Being older helps skin heal with less scarring, and now researchers know why University of Pennsylvania School of Medicine · Sep 26, 2018