Published in Science · View the paper (DOI)
Researchers used a combination of RoseTTAFold and AlphaFold to identify over 1,500 pairs of yeast proteins likely to interact. These complexes play roles in almost all key processes in eukaryotic cells, providing broad insights into biological function.
Coverage from 2 institutions
- Deep-learning in protein-protein interactions identifies complexes that will advance our understanding of cellular processes American Association for the Advancement of Science (AAAS) · Nov 11, 2021 · first to report
- Deep learning reveals how proteins interact University of Washington School of Medicine/UW Medicine · Nov 22, 2021