Add BrightSurf on Google Email

Targeting NAD+ regeneration enhances antibiotic susceptibility of Streptococcus pneumoniae during invasive disease

Home | Story
2 institutional releases

Published in PLOS Biology · View the paper (DOI)

Researchers found that fomepizole blocked energy production in bacteria and reduced bacterial burden in mice with pneumonia. The combination treatment prevented invasive disease development, suggesting a potential novel treatment for multidrug-resistant pneumococcal disease.

Coverage from 2 institutions

  • Fomepizole helps overcome antibiotic-resistant pneumonia in mice
    • Article 1 PLOS · Mar 16, 2023 · first to report
    • Article 2 University of Alabama at Birmingham · Mar 29, 2023