T cells specific for α-myosin drive immunotherapy-related myocarditis
2 institutional releases
Published in Nature · View the paper (DOI)
Researchers from Vanderbilt University Medical Center have identified the cardiac antigen α-myosin as the mechanism for immunotherapy-related myocarditis, a rare but deadly complication affecting less than 1% of patients. The discovery sets the framework to identify biomarkers and develop strategies to tolerate immunotherapy in at-risk...
Coverage from 2 institutions
- Cardiac antigen identified as mechanism for heart complication with immunotherapy-related myocarditis Vanderbilt University Medical Center · Nov 16, 2022 · first to report
- Myocarditis in cancer patients is driven by specific immune cells University of California - San Francisco · Nov 17, 2022