Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury

Published in Advanced Science · View the paper (DOI)

Researchers at CityU and HKUMed developed genetically modified human neural stem cells that promote neural circuit reconstruction, reduce glial scar accumulation, and enhance axon outgrowth. The therapy demonstrates potential for treating severe spinal cord injuries with functional recovery.

Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury

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