Published in Communications Biology · View the paper (DOI)
Researchers at Goethe University Frankfurt and University of Kent have discovered that the enzyme SAMHD1 can split phosphate groups off nelarabine, making it less effective in B-ALL patients. This breakthrough could lead to more targeted treatment options for individual patients.
Coverage from 2 institutions
- Treating leukaemia more effectively Goethe University Frankfurt · Jun 24, 2020 · first to report
- Decades old mystery in leukaemia treatment solved University of Kent · Jun 25, 2020