Published in Nature · View the paper (DOI)
A team of scientists has identified key mechanisms behind the triggering of the ribotoxic stress response, a protective program initiated in cells to remove damage or initiate cell death. The researchers found that protein ZAK plays a crucial role in mediating this stress response by recognizing collided ribosomes.
Coverage from 2 institutions
- Colliding ribosomes signal cellular stress Ludwig-Maximilians-Universität München · Nov 24, 2025 · first to report
- Scientists get detailed look at part of a cellular ‘stress’ warning protein Johns Hopkins Medicine · Nov 24, 2025