Researchers at Linköping University used magnetic cameras to examine blood flow in an artificial heart in real-time, revealing a pulsing pattern similar to that of a healthy heart. The study aims to design the heart to minimize complications such as blood clots and red blood cells breakdown.
Researchers developed mini biohybrid rays using cardiomyocytes and rubber, demonstrating improved swimming efficiencies approximately two times greater than previous biomimetic designs. The application of machine-learning directed optimization enabled an efficient search for high-performance design configurations.
A research team led by a physician-scientist found that artificial heart patients can regenerate heart muscle cells, which may lead to new ways to treat and potentially cure heart failure. The study showed that these patients' hearts regenerate muscle cells at more than six times the rate of healthy hearts.
Scientists at Queen Mary University of London have developed a new material that creates synthetic heart valves as effective as native ones. The innovative material, created by Dr Roberto Volpe, has anisotropic properties that mimic natural tissue and can be fine-tuned for rigidity and flexibility.
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Team Bath Heart, a team of students from the University of Bath, has won the second world Heart Hackathon title with their innovative artificial heart device. The team's prototype, which uses wireless charging and 3D printing, was praised for its novelty, progress, and presentation.
Researchers developed a tri-culture heart-on-a-chip model of cardiomyocytes, fibroblasts, and endothelial cells to mimic in vivo cardiac behavior. The study successfully replicated endothelial cell morphology and functionality, as well as cardiac function with increased contractility.
A multi-institutional team is creating innovative technologies to reduce complications associated with left ventricular assist devices (LVADs), including infection, thrombosis, stroke, and bleeding. The new LVAD will deliver a physiological response to changes in the recipient's activity levels using a 'smart' Maglev drive technology.
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Researchers at Harvard developed a fiber-infused ink that allows 3D-printed heart muscle cells to align and contract like human heart cells, enabling the creation of functional heart ventricles. The innovation can be used to build life-like heart tissues with thicker muscle walls, paving the way for regenerative therapeutics.
The PULSE project combines magnetic and acoustic levitation to bioprint highly sophisticated organoids that closely mimic human organs. These in vitro heart models will provide invaluable insights into cardiac physiology and pathology, enabling the development of preventive and therapeutic solutions.
Researchers have developed a new manufacturing pipeline to simplify and advance high-value manufacturing of tissue-compatible organs, reducing costs and increasing efficiency. This breakthrough aims to address the dire need for artificially engineered organs and tissue grafts, potentially saving thousands of lives in the UK.
Bioengineers from Harvard John A. Paulson School of Engineering and Applied Sciences create first biohybrid model of human ventricles with helically aligned beating cardiac cells, increasing blood pumping efficiency by up to 50%. The model was made possible using Focused Rotary Jet Spinning (FRJS), a new method of additive textile manu...
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A team of researchers has successfully created complex artificial tissue models, including a full-scale human heart model, using focused rotary jet spinning. This method enables the creation of intricate details and spatially varying alignment, rivaling biological tissues in mechanical behavior.
Researchers developed a fully autonomous biohybrid fish from human stem-cell derived cardiac muscle cells that recreates the muscle contractions of a pumping heart. The device has two layers of muscle cells that work together to propel the fish for over 100 days.
A new imaging technique can detect early signs of blood trauma in red blood cells, which could aid in the development of markers to prevent damage. The technique, developed by researchers at Shibaura Institute of Technology and Griffith University, uses high-speed cameras to visualize changes in RBC shape under stress.
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The Carmat Total Artificial Heart (CTAH) has shown promising results in its 'Auto-Mode' feature, which adjusts to changing patient needs. This allows for minimal device management changes and potentially improves quality of life for patients with end-stage heart failure.
Researchers at ETH Zurich developed a soft artificial heart made from silicone that mimics the human heart's form and function. The device lasts only 3,000 beats but paves the way for future improvements in artificial hearts.
New supercomputer models capture normal human heart valves' behavior and their replacements, helping doctors make more durable repairs. The models can simulate the effects of realistic blood flow on heart valve tissue, allowing for better understanding of valve failure mechanisms.
Researchers found that five out of 22 patients implanted with total artificial hearts survived until they could receive a heart transplant, with four successfully undergoing transplants and 13 still alive waiting for donor hearts. The study suggests the device may help improve patient outcomes for those in end-stage heart failure.
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Researchers have created an artificial heart that can pump human waste into future robots, powering eco-friendly systems. The device uses shape memory alloys to mimic the human heart's pumping action and is more mechanically simpler than conventional pumps.
Researchers at Brigham and Women's Hospital developed a new material called MeTro gel that mimics the elasticity of human tissues. The material was used to create artificial heart tissue with beating muscle cells, which could potentially advance treatments for heart disease.
Researchers at Northwestern Memorial HealthCare have successfully implanted two small Heartware VADs in a 44-year-old patient with severe myocarditis, marking the first time this biventricular approach has been used in the US. The device provides total heart support without removing the patient's natural heart.
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The VCU Medical Center is leading a national clinical trial of a portable, mechanical driver that can power patients' artificial hearts outside the hospital environment. The device allows stable patients to recuperate in their own homes until a donor heart becomes available for transplant.
The US FDA has approved a new totally implanted artificial heart, providing hope for patients with severe heart failure. The device is designed for those who are not eligible for a heart transplant and have a short life expectancy without the device.
Hassan Khalil's model will allow for new experimentation in artificial organ control, making experiments more flexible and predictable. The collaboration between UH and the Texas Medical Center fosters collaborations between engineers, doctors, and professionals.
A recent study supports the use of mechanical assistance as a standard of care for treating acute and chronic heart failure, particularly in high-risk patients. The findings have implications for funding artificial heart programs, increasing access to this life-saving treatment.
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Scientists at Penn State have developed a new method to reduce the permeability of biomedical polymers using silicate clay, achieving a significant improvement in air and water resistance. The clay is mixed with the polymer in a common solvent, resulting in a barrier that effectively blocks many paths for air and water migration.
Case Western Reserve University researchers are developing a new method to study blood flow through artificial heart components by mimicking the behavior of coal water slurries. This approach has revealed the importance of particle distribution and velocity in preventing blood clots, which can lead to stroke and death.
Researchers are working on long-term artificial heart replacement devices that can be used in humans within five years. Temporary ventricular assist devices have saved thousands of lives and continue to be a major part of heart replacement research.
Researchers at Penn State's Milton S. Hershey Medical Center are developing an electromechanical artificial heart to save thousands of lives. The device is expected to be widely available by 2005 and could implant over 50,000 patients per year.