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5-aminolevulinic acid might help fight mitochondrial disorders

Researchers at Tokyo Metropolitan University have discovered that 5-aminolevulinic acid can selectively boost Complex II and IV to counteract Complex I deficiency, a common cause of mitochondrial disorders. This finding offers new hope for the development of treatments for debilitating conditions such as MELAS syndrome.

Metabolic acidosis associated with an increased mortality rate

A study of 851 patients found that metabolic acidosis was associated with a higher mortality rate compared to non-acidosis patients. Lactic acidosis and SIG acidosis were identified as independent predictors of hospital mortality in critically ill patients.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.