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The biggest isn't always best when it comes to treating cancer

Researchers found that vaccines inducing intermediate T cell responses effectively protected mice from tumor growth, while those with high responses did not. The study suggests re-evaluating the role of T cell response magnitude in vaccine development.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 24, 2006
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JCI table of contents: August 24, 2006

Researchers have made significant breakthroughs in cancer vaccine development and cardiac health. A study on mice vaccinated with mimotopes inducing intermediate magnitude T cell responses found protection against tumor growth, while a study on Casq2-deficient mice revealed the mechanisms behind irregular heartbeats during exercise.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 24, 2006