Antiapoptotic Proteins | Topics

Articles tagged with Antiapoptotic Proteins

Cancer: Trapping the escape artist

Recent discoveries may help curb anti-apoptotic proteins that tumors express to resist treatment. Researchers outline how six anti-apoptotic proteins in the Bcl-2 family are expressed differently in different cancers.

SourceSanford Burnham Prebys·JournalCell Death and Disease·DateMay 11, 2010

Chemosensitivity of cancer cells depends on their protein dependency

Researchers found that leukemia cells reliant on MCL-1 are more sensitive to chemotherapeutic drugs than those dependent on BCL-2. A block in apoptosis selected during oncogenesis can significantly impact cancer's response to chemotherapy.

SourceRockefeller University Press·JournalJournal of Cell Biology·DateOct 26, 2009

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