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Scientists improve the equation in FDA guidance predicting drug interactions

Researchers have improved the FDA's equation for predicting drug interactions by addressing fundamental limitations and incorporating new models. The modified equation has shown a significantly increased accuracy of about 80%, which is expected to contribute to increasing the success rate of new drug development.

SourceInstitute for Basic Science·JournalClinical Pharmacology & Therapeutics·TypeComputational simulation/modeling·DateJan 12, 2023