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GZ17-6.02 kills PDX isolates of uveal melanoma

Researchers found that GZ17-6.02 killed uveal melanoma cells by enhancing autophagy, inactivating key proteins, and reducing growth factors. The compound also interacted with doxorubicin and ERBB inhibitors to enhance tumor cell killing, suggesting potential as a single agent or combination therapy.

SourceImpact Journals LLC·JournalOncotarget·TypeExperimental study·DateMay 22, 2024