G Proteins | Topics | BrightSurf

Articles tagged with G Proteins

Bias can lead to better therapies

Researchers at Sanford Burnham Prebys discovered a new mechanism to confer signaling bias in predictable ways, permitting rational design of new drugs. This breakthrough could lead to better therapies for addiction and psychiatric disorders by targeting the neurotensin receptor 1 (NTSR1) with biased modulators.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Elucidating the complex structure of the blood vessel contraction factor endothelin, its receptor protein, and G protein

The study uses cryo-electron microscopy to observe the ETB receptor-G protein complex, revealing a strong binding interaction between G protein and ETB receptor. This finding may deepen understanding of endothelin signaling mechanisms and inform the development of new drugs.