Articles tagged with Lysozymes
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study reveals that oral lysozyme can restore a healthy gut balance and reverse signs of vascular aging in older adults. The research identifies the PI3K–Akt signaling pathway as a key mediator, suggesting new lines of research into metabolites and microbial strains for vascular health.
Researchers identified a gut-lung axis driven by intestinal antimicrobial peptide expression and mediated by the intestinal microbiota that influences hyperoxia-induced lung injury. Supplemental lysozyme reduced lung injury in neonatal mice, suggesting a potential therapeutic target.
Researchers developed a novel hybrid protein complex by binding lysozyme to copper for enhanced reactive oxygen species (ROS) removal. The CuST@lysozyme hybrid protein showed high SOD activity and stability in biological fluids, paving the way for its therapeutic applications.
Researchers have developed a novel technology for nanoencapsulation of bioactive compounds, specifically anthocyanin, using pectin and lysozyme. The methodology ensures slow release of the compound, allowing it to survive gut bacteria and digestive enzymes.
Scientists developed an AI system, ProGen, that can generate artificial enzymes from scratch, working as well as those found in nature. The AI model learned aspects of evolution and was able to tune its generation for specific effects, creating proteins with unique properties.
A new study found that a subtilisin-like proteinase from Bacillus pumilus 3-19 exhibits proteolytic activity in Pichia pastoris, dependent on incubation time and signal peptide choice. The production of this enzyme makes the system promising for developing new feed additives for animal husbandry.
Researchers have identified a unique enzyme used by predatory bacteria to rupture the cell wall of its prey bacteria and exit without damaging its own cell wall. The discovery of this novel lysozyme holds promise for developing new therapies against antibiotic-resistant pathogens.
The team used terahertz-frequency light to probe the vibrational modes of lysozyme, discovering that its glassy and fractal nature explains the anomalously large vibrations. The study may lead to improvements in industrial glass manufacturing by understanding disordered materials.
A Rutgers-Newark study discovered that lysozyme in the gut stimulates inflammation in some people with ulcerative colitis, leading to ulcers and sores in the large intestine. The study may help develop future treatments for inflammatory bowel disease by gaining insights into immune balance.
Researchers developed a fluorescence-based technique to monitor single molecules, accelerating structural biology and potentially aiding in structure-guided drug design. The technique uses FRET to visualize biomolecules with unprecedented spatial and temporal resolution.
Gonorrhea researchers have identified a novel protein that powers the virulence of the bacteria causing gonorrhea, opening the possibility of a new target for antibiotics. The discovery could lead to the development of a vaccine and improved treatment options for the highly damaging disease.
Researchers at Newcastle University have identified how lysozyme and penicillin work together to cause recurrent infections, shedding light on why some patients become resistant to antibiotics. The study also reveals the formation of L-forms, bacteria that can grow in human tissue without cell walls, leading to recurring infections.
Scientists from Ural Federal University and the University of Limerick proved that lysozyme exhibits piezoelectric properties, generating electric charges that can power pacemakers and stimulate nerve endings. This discovery has implications for various biomedical applications, including biosensors for disease detection.
Researchers at the University of Limerick have discovered that applying pressure to crystals of lysozyme, a protein found in egg whites and tears, can generate electricity. This finding has significant implications for innovative applications such as electroactive coatings for medical implants.
Proteins' tiny motions, called vibrations, enable interactions with other molecules. A new study shows that the direction of these vibrations matters more than previously thought, shedding light on how proteins interact and facilitating tasks like absorbing oxygen and repairing cells.
Researchers found that lysozyme increases in the brains of Alzheimer's patients and has favorable effects on fly models of the disease. The findings indicate that lysozyme may represent a clinical marker for Alzheimer's and a potential therapeutic strategy to slow disease progression.
Researchers at SLAC's Linac Coherent Light Source (LCLS) X-ray laser used the technique to generate an accurate model of lysozyme, a well-studied enzyme found in egg whites. The study opens the door to new discoveries and explores the potential for LCLS to play a leading role in studying important biomolecules of unknown structure.
A study found that colistin resistance in bacteria also makes them resistant to the human immune system's defense mechanisms, such as LL-37 and lysozyme. This cross-resistance increases the risk of complications for patients with life-threatening multi-drug resistant infections.
Researchers at UC Davis found that goats' milk carrying higher levels of the antimicrobial protein lysozyme successfully treated diarrhea caused by bacterial infection in young pigs. The study suggests that such milk may eventually help prevent human diarrheal diseases, which claim millions of lives annually.
An international team led by SLAC National Accelerator Laboratory has used the world's most powerful X-ray laser to obtain ultrahigh-resolution views of nano-crystals of biomolecules, including a small protein found in egg whites. This technique enables researchers to view molecular dynamics at a time-scale never observed before.
Scientists used a novel X-ray technique to analyze the structure of hen egg white lysozyme at a high resolution of 0.19 nanometres, demonstrating the potential of free-electron lasers in structural biology. The technique, which uses ultrashort X-ray pulses, enables the study of previously intractable molecular structures.
Scientists have successfully imaged biomolecules at individual atom level using X-ray lasers, enabling new avenues for biological research. The technique, known as serial femtosecond crystallography, has been used to study a small protein called lysozyme and holds promise for understanding complex biological systems.
Purdue University scientist Kevin Keener's research suggests that rapidly cooling eggs can increase the activity of lysozyme, an enzyme that defends egg whites from bacteria. By re-saturating egg whites with carbon dioxide and altering pH levels, the technology aims to create a safer food product.
An antibacterial enzyme found in human tears and body fluids, lysozyme has the potential to eliminate anthrax-producing bacteria from processed foods. The study shows that lysozyme application can kill Bacillus anthracis spores, including avirulent forms.
Researchers at the University of Oregon have successfully demonstrated that specially synthesized boron compounds can be accepted by biologically active enzymes. This breakthrough could lead to new drug design strategies and boost boron's expanding use in medicine.
Cystic fibrosis patients may benefit from a new therapeutic strategy that targets deadly bacterial infections by manipulating the binding of antimicrobials in mucus. By reducing the charge on lysozyme, researchers found it could float independently in the mucus and kill bacteria effectively.
A new protein, Lyz, has been discovered to transform into a different structure, enabling medical researchers to design drugs that can turn proteins on or off at the cellular level. This discovery could lead to treatment for difficult-to-cure diseases such as cancer and HIV.