Articles tagged with Netrins
Researchers at Kanazawa University found that a neuroscience-protein regulates brain boundary formation in fly brains by exchanging with its partners between neurons and glial cells. The protein's balance of attraction and repulsion regulates boundary formation.
Researchers at Rockefeller University discovered a new signaling molecule, NELL2, that guides axons during critical brain development. The molecule directs commissural axons to the midline using Robo3 receptors, shedding light on axon guidance and potential treatments for horizontal gaze palsy with progressive scoliosis.
Researchers at Duke University have uncovered a 'roving detection system' on cell surfaces that may lead to new cancer therapies. The system involves receptors that search for signals to guide cell movement, potentially allowing for the prevention of metastasis and other diseases.
Researchers have solved a longstanding puzzle in neuroscience by revealing the three-dimensional atomic structure of netrin-1, a guidance protein that can attract or repel brain cells. By understanding how this protein works, scientists may be able to develop new ways to steer cell behavior and potentially treat diseases such as cancer.
Researchers discovered a novel conceptual framework that explains how neurons establish spatial polarity and direction using netrin and Wnt signaling pathways. The study found that these pathways work redundantly in guiding cell migrations along different axes.
A new study from McGill University reveals that the DCC receptor is essential for normal synaptic function and plasticity, leading to progressive degeneration of synapses and defects in memory formation. The absence of DCC leads to memory loss similar to Dr. Brenda Milner's famous subject HM.
Netrins, a family of proteins, accelerate blood vessel growth and restore nerve growth in ischemic and diabetic mice. This breakthrough has significant implications for treating diabetes and peripheral vascular disease.
Researchers at the MNI have made a groundbreaking discovery about netrins, proteins that guide nerve cell axons to their target in the developing nervous system. The study suggests that netrin acts as a repellent cue for migrating oligodendrocytes, which could lead to new therapies for Multiple Sclerosis.
Researchers discover that nerve cells use chemical scissors to clip off axon guidance receptors, controlling their navigation in the nervous system. Metalloprotease inhibitors enhance netrin activity by blocking receptor cleavage.