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Evidence of harmful effect of bisphenol A-based plastics

Researchers have found that bisphenol A impairs the function of vital proteins in cells, suggesting a potential health risk. The study also discovered alternative compounds with promising applications in cancer treatment.

SourceRuhr-University Bochum·JournalJournal of Medicinal Chemistry·DateJan 10, 2014

NRH1 and Wnt signaling come together in convergent extension

Researchers identified NRH1 as essential for regulating convergent extension in frogs, a process also influenced by Wnt/PCP signaling. Overexpression of NRH1 resulted in shortening of the body axis and failure of mesodermal marker gene expression, while loss-of-function led to inhibition of convergent extension.

SourceRIKEN Center for Developmental Biology·JournalNature Cell Biology·DateJul 20, 2004