Articles tagged with Vasopressin
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The European Society of Endocrinology is launching a new campaign to raise awareness about the importance of hormone health. The #BecauseHormonesMatter initiative aims to improve public understanding of hormones and promote practical steps for better hormone health, following the success of last year's campaign.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Scientists have identified the mechanism linking a mutation in the Shank3 gene with alterations in social behavior, revealing that vasopressin plays a crucial role in regulating sociability and aggression. The study shows that targeting specific vasopressin receptors can restore social abilities without affecting aggression.
A human study found that ultra-processed diets lead to increased weight gain, disrupt hormone levels, and introduce pollutants affecting sperm quality. Men on an ultra-processed diet gained more fat mass and had lower testosterone and follicle-stimulating hormone levels compared to those on a minimally processed diet.
The EndoCompass project aims to guide future studies and funding programs with a research roadmap for better hormone health in Europe. Manuel Heitor will share his perspective on the future of research in Europe, emphasizing the need for greater investment and coordination.
The Texas Tech University Health Sciences Center is conducting a randomized controlled trial to investigate the effectiveness of calcium and vasopressin in treating severely injured patients who experience significant blood loss. The study, known as CAVALIER, will enroll approximately 1,050 participants aged 18-90.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
A team of researchers from Kyoto University found that the pituitary vasopressin system is crucial for building a robust circadian clock in the suprachiasmatic nucleus. This discovery has led to the development of potential treatments for jet lag, which currently target only the suprachiasmatic nucleus.
Excessive fluid consumption can be caused by a rare hormone deficiency, polyuria-polydipsia syndrome, which regulates the body's water and salt content. Researchers have developed a reliable test using highly concentrated salt infusion to diagnose this condition.
Researchers have demonstrated a clinically relevant oxytocin deficiency in patients with vasopressin deficiency, which could lead to new therapeutic approaches for conditions like autism.
The August issue of the CHEST journal features 47 articles on clinically relevant topics such as asthma, COPD, and pulmonary vascular disease. A highlighted article examines barriers to palliative care in interstitial lung disease.
A team of Georgia State researchers used CRISPR-Cas9 technology to eliminate the Avpr1a receptor in hamsters, leading to unexpected changes in their social behavior. The study found that knocking out the receptor increased social communication behaviors and eliminated sex differences in aggression.
A new study suggests that a high-salt diet can lead to the hyperactivity of brain cells, resulting in increased constriction of blood vessels and worsening of cardiometabolic diseases. The research also found that excessive salt consumption can trigger an unusual response in which neurons become more active despite reduced blood flow.
A study published in Hypertension reveals that vasopressin receptor stimulation leads to the short-term secretion of uromodulin into the urine in mice. Higher levels of uromodulin are associated with lower rates of urinary tract infections and kidney stones.
Scientists have created a detailed map of the mouse brain's oxytocin-vasopressin circuit, revealing dynamic adaptations that refine neural circuits during development. These findings may underlie social disorders such as autism and schizophrenia.
A new study comparing lemurs, distant primate cousins of humans, found few consistent differences between monogamous and promiscuous species. However, researchers discovered that the brain chemistry behind love in lemurs may involve a combination of multiple hormones and interactions rather than a single formula.
Researchers from MedUni Vienna and University of Vienna develop new oxytocin/vasopressin constructs with enhanced efficacy, inspired by naturally occurring dimers like locust neuropeptides. These bioactive molecules offer opportunities to optimize therapeutic application for various disorders.
Researchers found that water suppresses vasopressin, a hormone linked to obesity and diabetes, alleviating conditions in mice. Water therapy effectively protected against metabolic syndrome, a collection of conditions increasing the risk of heart disease and type 2 diabetes.
A study led by Stanford researchers found that low levels of the hormone vasopressin in infants' cerebrospinal fluid may predict an autism diagnosis. The findings suggest that early intervention could be beneficial for affected children.
Research identifies lower concentrations of neuropeptide arginine vasopressin in infant cerebrospinal fluid of those diagnosed with autism spectrum disorder. This finding suggests a potential biomarker for early detection and prediction of the disorder.
Recent research from Dr. Dan Krawczyk's lab at the Center for BrainHealth explored the effects of oxytocin and vasopressin on social cognition. Oxytocin consistently led a perception of greater dominance, while both hormones affected brain activity across trustworthiness and dominance.
Two clinical trials found that modulating the vasopressin hormone's biological pathway enhanced social functioning in adults and children with ASD. The studies showed improvements in social behavior, adaptive skills, and reduced anxiety symptoms in treated individuals.
Researchers have identified a brain region that controls both social memory and aggression, revealing a complex link between the two behaviors. The discovery sheds light on psychiatric disorders such as schizophrenia, where altered CA2 function may contribute to abnormal social behaviors.
A study by Penn State found that adults who sleep six hours per night have significantly more concentrated urine and higher odds of dehydration compared to those who sleep eight hours. This is due to the body's hormonal system regulating hydration, particularly the hormone vasopressin.
A new procedure has been developed to quickly diagnose drinking by the liter, a condition that can be caused by rare hormone disorders like diabetes insipidus. The test, which measures biomarkers in blood, has a high diagnostic accuracy and can treat patients with primary polydipsia through behavioral therapy.
A study found that oxytocin and vasopressin reduce aggression and increase cooperation in male rhesus macaques, flattening the social hierarchy and promoting egalitarian behavior. The hormones also synchronize behaviors, enabling non-verbal communication between animals.
A new study links low vasopressin levels in cerebrospinal fluid to impaired social abilities in monkeys and children with autism, suggesting a potential biomarker for the condition. The researchers hope to further explore the hormone's role in autism diagnosis.
Researchers discovered that rhesus macaques and children with autism spectrum disorder have lower vasopressin levels, linked to reduced sociability. The study suggests vasopressin as a potential biomarker for social deficits in autism.
A study on Caenorhabditis elegans reveals a gene that regulates exploration and homeboding in worms, which also exists in the human genome. This gene responds to adrenaline and is linked to behavior in mice, with implications for understanding parental behavior in humans.
Researchers discovered vasopressin's role in stimulating red blood cell production, with implications for treating anemia after traumatic injuries or chemotherapy. The hormone's effectiveness was demonstrated in mouse models and clinical data from patients with central diabetes insipidus.
Dr. Charles Bourque's research reveals vasopressin's role in regulating body hydration and its link to various health problems, including congestive heart failure and salt-dependent hypertension. The molecule is also involved in feed-forward mechanisms, producing anticipatory signals before sleep and dehydration.
A study by McGill University researchers found that the brain's biological clock regulates thirst in the hours leading up to sleep. By stimulating vasopressin release, the clock anticipates dehydration and increases water intake.
Researchers compared early treatment with vasopressin to norepinephrine in septic shock patients, finding that neither improved kidney failure-free days. The study suggests that larger trials may be needed to assess potential benefits of alternative treatments.
A new study found that vasopressin increases placebo analgesic effects in women, particularly those with lower acute stress and anxiety. The findings suggest a new mechanism for the neurobiology of placebo effects and open up research directions for understanding the vasopressin system.
A new study from Stanford University School of Medicine suggests that low levels of vasopressin, a hormone involved in social behavior, are associated with social deficits in children with autism. Researchers found that autistic children who had the lowest vasopressin levels in their blood also displayed greater social impairment.
Researchers explored connection between empathy, neurohormones and aggression. Empathy can motivate aggression on behalf of vulnerable others, even without provocation. Neurohormone gene variants, such as vasopressin and oxytocin, interact to predict aggression in these situations.
Temple University researchers discovered a promising new target for treating end-stage heart failure by blocking the vasopressin type 1A receptor, which interferes with the heart's ability to receive important signals. The finding could lead to more effective therapies and improve symptoms in patients with heart failure.
A recent study found that vasopressin alone or in combination with epinephrine suppresses neuronal apoptosis and activates anti-apoptotic pathways during cardiopulmonary resuscitation. This suggests a potential benefit of vasopressin for improving CPR outcomes.
Researchers at Georgia State University have discovered that chimpanzees exhibit similar personality traits to humans, including dominance and extraversion. The study's findings suggest a neurobiological basis for these traits, which vary according to biological sex, echoing the five-factor model of human personality.
A new study found that genes related to oxytocin and vasopressin receptors influence prosocial behavior, particularly in people who perceive the world as threatening. However, there was no direct connection between genes and charitable or social attitudes.
Research by psychologists at the University at Buffalo found that certain genes associated with niceness can influence behavior, particularly in response to perceived threats. The study suggests a genetic component to kindness, which can vary depending on individual experiences and perceptions of the world.
Researchers found vasopressin in brain prevents neuronal swelling by maintaining neuron size, contrasting with kidney function. This discovery may aid in treating cerebral edema conditions, such as those caused by brain trauma or infarction.
Researchers at LSU Health Sciences Center New Orleans have discovered that two brain proteins, Gαq and Gαz, act as valves to regulate vasopressin secretion and water retention in salt-sensitive hypertension. This finding may lead to new treatment options for high blood pressure, congestive heart failure, and cirrhosis of the liver.
Researchers discovered NG peptides in marine animals, similar to the mutant gene causing diabetes insipidus, providing new understanding of a rare form of diabetes. The discovery could help explain symptoms and treatment for around 10,000 people in the UK.
Researchers at the University of Edinburgh found that the hormone vasopressin plays a crucial role in helping animals recognize others through scent. This ability is essential for establishing strong bonds with other animals, and its failure may contribute to conditions like autism and social phobia.
The new vaptan drug class has shown promising results in treating conditions such as painful periods, brain hemorrhage, and psychotic disorders. The drugs target the vasopressin hormone system, inducing water loss without mineral salt loss, to treat various health issues.
Scientists studied prairie voles' mating habits and nervous systems to understand their behavior. The research found that male 'wanderers' lack receptors for spatial memory, leading them to return to territories with high contact with females.
Researchers found vasopressin significantly reduces blood flow to vital organs like the liver and pancreas, but not the heart. The study used pigs to test vasopressin's effects on sepsis and found severe disturbances in blood flow.
A new study suggests that lixivaptan, a drug blocking vasopressin, is as effective as diuretics in reducing fluid retention in patients with congestive heart failure while also retaining proper sodium levels. The drug may offer an alternative treatment for heart failure patients and help clarify the role of vasopressin in water retention.
Research at the University of Wisconsin-Madison found that children who experienced early neglect have lower levels of vasopressin, a hormone essential for recognizing familiar individuals. This hormonal imbalance may contribute to difficulties in forming secure relationships later in life.
Researchers found that including choline in baby formula during pregnancy can prevent symptoms of Fetal Alcohol Syndrome, a condition causing learning disabilities and mental retardation. The study also suggests that monitoring infants' urine flow and vasopressin content could serve as future tests for the condition.
Researchers found that Viagra can stimulate water permeability in kidney cells by increasing cyclic-GMP levels, potentially alleviating symptoms of nephrogenic diabetes insipidus. Long-term studies are needed to confirm the effectiveness and safety of this approach.
A study by Emory University researchers has found that variations in microsatellite sequences of the vasopressin receptor gene can influence social behavior and parenting behaviors in voles. These findings suggest that junk DNA may play a role in shaping individual differences and social diversity.
Researchers discovered a new genetic disease, Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD), in two infants who were retaining excess fluids and diluting sodium levels in their blood. The condition is caused by mutations in the AVPR2 gene that affects vasopressin binding, leading to inappropriate antidiuresis.
By transferring vasopressin receptor genes into meadow voles, scientists observed a strong preference for current partners, mirroring the behavior of prairie voles. This study provides evidence that changes in a single gene can profoundly impact social behavior in animals.
Research by Emory University Health Sciences Center suggests that reward mechanisms involved in addiction likely play a role in regulating pair bonds between monogamous animals. The study found that oxytocin and vasopressin receptors, critical for pair bond formation, are located in two brain regions with heavily interconnected structu...
Researchers found that prenatal ethanol exposure led to partial central diabetes insipidus in young adult rats, characterized by increased water consumption and reduced vasopressin release. This finding may provide insight into the pathogenesis of diabetes insipidus and offer potential treatment targets for this debilitating disorder.
Researchers used gene transfer to increase vasopressin receptor density in the ventral pallidum of prairie voles, leading to increased pair bonding. The study shows that higher levels of vasopressin receptor expression are associated with more affiliative behavior and stronger pair bonds.
Scientists at Emory University create transgenic mice with a prairie vole vasopressin receptor gene, showing increased social behavior and adopting gregarious behaviors. The study provides an explanation for the species difference in receptor distribution and its impact on social behavior.