Articles tagged with Muscle Contraction
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Researchers discovered that inhibiting a protein called RBM20 can improve heart filling and flexibility in mice with heart failure. The study also found positive impacts on energy metabolism, mitochondrial function, antioxidant balance, and blood flow.
A recent study using Drosophila as a model organism reveals the involvement of linear ubiquitination in T-tubule biogenesis. The findings highlight LUBEL's role in triggering Amph-mediated T-tubule formation, which promotes membrane tubulation and curvature through self-ubiquitination and positive feedback loops.
A recent study from Harvard John A. Paulson School of Engineering and Applied Sciences uses wearable sensor technology and machine learning to estimate ground-reaction forces in runners. This data can provide insights into performance and injury, enabling the development of devices that deliver real-time feedback to users.
A genetically engineered mouse model shows RyR1-mediated calcium-induced calcium release plays a minimal role in normal skeletal muscle contraction, but is crucial in life-threatening muscle disorders. The study confirms depolarization-induced calcium release as the main driver of muscle contraction.
A UCLA team has uncovered new details about the muscle controlling blinking, offering a pathway toward developing blink-assisting prostheses. The orbicularis oculi muscle contracts in complex patterns that vary by action and move the eyelid in more than just a simple up-and-down motion.
Researchers reanalyzed the coelacanth's skull musculature and found that only 13% of previously identified evolutionary muscle novelties were accurate. The study also identified nine new evolutionary transformations related to feeding and respiration, revealing a more similar anatomy to cartilaginous fish and tetrapods.
A new study reveals that myosin binding protein-C (cMyBP-C) is essential for regulating cardiac muscle contraction, particularly under increased stress. The protein's absence or mutation can lead to diseases such as heart failure and hypertropic cardiomyopathy.
Northern Arizona University researchers have developed an open-source robotic exoskeleton framework, OpenExo, which provides comprehensive instructions for building single- or multi-joint exoskeletons. The system helps overcome challenges in developing biomechanically beneficial and technologically advanced exoskeletons.
Researchers discovered bombesin-like peptides in the body can trigger contractions in the vas deferens, a muscular tube carrying sperm in the male reproductive system. The peptides likely act through a specific receptor to induce contractions.
A team of researchers from Osaka University has demonstrated that human tissue can be used to solve complex equations and process information, outperforming traditional computing methods. This breakthrough uses the concept of reservoir computing, where data is input into a complex 'reservoir' that encodes rich patterns.
A study published in Nature Communications found that the fastest animals are medium-sized, like cheetahs, due to a physical limit imposed by muscle contraction speed and shortening. This sweet spot size of around 50kg enables animals to reach speeds of up to 65 miles per hour
Researchers at Waseda University used diffusion tensor imaging to reconstruct fascicles in three dimensions, finding that a gearing mechanism reduces individual fascicle elongation during stretching. This mechanism allows muscles to extend without significant fiber length changes, preventing overstretching and injury.
Researchers at Max Planck Institute of Molecular Physiology developed an innovative imaging technique to visualize the cardiac thick filament in its native environment. The resulting high-resolution image reveals new insights into the molecular organization and function of the sarcomere, a crucial component of heart muscle contraction.
The Kessler Foundation will evaluate the long-term effects of a myoelectric orthosis on improving hand/wrist/elbow capability in individuals with spinal cord injuries. The goal is to increase muscle strength, joint range of motion, and daily task ability.
Researchers developed a fully autonomous biohybrid fish from human stem-cell derived cardiac muscle cells that recreates the muscle contractions of a pumping heart. The device has two layers of muscle cells that work together to propel the fish for over 100 days.
Scientists from the University of Tsukuba analyzed video from top-level judo matches to systematically determine the aspects of posture that lead to success. The study found that the distance between competitors is a key factor in correct technique, which may assist in automating athletic training methods.