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Introducing a kinder, gentler way to blow holes in cells

Scientists have developed a kinder gentler way to deliver big molecules like Cas9 enzyme into cells, improving efficiency and safety. The new technique, nanopore-electroporation, creates fewer than a dozen tiny holes in each cell, allowing for more effective gene editing and delivery of therapeutic proteins.

SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateMar 28, 2019

Story ideas from Molecular & Cellular Proteomics

Researchers have identified new proteins in amniotic fluid that could improve pregnancy marker development. Additionally, a study on the Wlds gene has provided insights into preventing neuronal communication deterioration in Alzheimer's disease. A comprehensive analysis of proteins in human Jurkat T cells has also been conducted.

SourceAmerican Society for Biochemistry and Molecular Biology·JournalMolecular & Cellular Proteomics·DateAug 22, 2007

Retroviral protein triggers proliferation of immune cells

The study reveals that retroviral protein p12 stimulates the growth and proliferation of immune cells known as T lymphocytes by producing interleukin 2 (IL-2). This finding supports the view that HTLV-1 virus replicates mainly by causing infected cells to divide and proliferate.

SourceOhio State University·JournalJournal of Virology·DateOct 22, 2003