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New study on the circadian clock of the fruit fly

Researchers discovered a point mutation in the fruit fly Drosophila melanogaster that leads to a temperature-dependent lengthening of circadian clock periods. The mutation affects the nuclear export signal of the PERIOD protein, resulting in its retention in the cell nucleus at higher temperatures.

Nuclear export of opioid growth factor receptor is CRM1 dependent

Researchers at The Pennsylvania State University College of Medicine discovered that the nuclear export of the opioid growth factor receptor (OGFr) is CRM1 dependent. OGFr must translocate into the nucleus to facilitate its role in cell cycle regulation and does so utilizing nuclear localization signals and β and Ran proteins.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.