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Power to the genome: Scientists decipher how the nucleus gets its energy

A groundbreaking study identifies a direct energy route between mitochondria and the nucleus, supporting gene regulation, chromatin remodeling, and cell differentiation. The finding challenges traditional assumptions about energy transfer in cells and has significant implications for understanding health and disease.

A broken DNA repair tool accelerates aging

A Goethe University-led study reveals how mutations in the SPRTN enzyme cause chronic inflammation and premature ageing. The research team found that damaged DNA in the cell nucleus leaks into the cytoplasm, activating defense mechanisms and leading to chronic inflammation.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Obesity: A discovery shakes 60 years of certainty about fat metabolism

Researchers have discovered that HSL plays an unexpected role in the nucleus of fat cells, helping maintain healthy adipose tissue. This new understanding challenges 60 years of certainty about fat metabolism and offers avenues for better understanding metabolic diseases such as obesity.

Of hearts and giants: Moving a cardiac regulatory protein to the right place

International researchers led by Tokyo Medical and Dental University investigated the RSRSP stretch of the regulatory protein RBM20, finding it essential for nuclear localization and splicing regulation. The study suggests that phosphorylation of specific serine residues in this region is crucial for RBM20's function.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Wnt signaling in polarized cell divisions

Recent research has shed light on the mechanisms underlying Wnt signaling in polarized cell divisions. The study reveals that Wnt signaling regulates cell fate and tissue organization by controlling the asymmetric division of stem cells.