Phosphorylation State | Topics

Articles tagged with Phosphorylation State

Revealing an invisible kinase state that accounts for vital biological function

Researchers characterized a hidden intermediate state in Src kinase function, which enables rapid phosphorylation and is essential for T-cell activation and cell migration. This study expands our understanding of kinase function and sets the stage for new therapeutic approaches that selectively target these conformational states.

Reporters broadcast live, on-the-scene, inside living cells

Researchers from Rice University and Princeton University have developed a new technology that allows for the live monitoring of signaling protein networks in living cells. The 'live reporter' system uses unobtrusive proteins to tag specific proteins, which can activate fluorescent markers when they become phosphorylated.

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