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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

New insights into harmful mutations in sperm

A recent study led by Harvard Medical School researchers found that genetic changes creating identical sperm cells are more widespread than thought and linked to single-gene diseases. The team identified genes underlying these mutations, which can be passed onto offspring, leading to devastating disorders.

Battle of the sex chromosomes

A study from Michigan Medicine researchers reveals that X-carrying and Y-carrying sperm compete for binding to Spindlins, influencing gene expression and the sex ratio. The findings suggest that this competition is crucial for maintaining the optimal balance of female and male offspring in mice.

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Same genes that made gorilla penises small may make men infertile

A University at Buffalo-led research team has found that the same genes whose mutations gave rise to a low functioning male gorilla reproductive system may also be responsible for human male infertility. Researchers identified 109 reproductive-related gorilla genes that are often mutated when present in infertile men.

Male beetles neglect their genomes when competing for females

In a 50-generation evolutionary experiment, male beetles from lineages with intense sexual selection produced lower quality offspring after DNA-damaging radiation. This suggests that males invest more in competition at the expense of DNA repair, impacting future offspring survival and fertility.

Sperm or eggs? How hermaphroditic worms distribute their resources

Researchers discovered two dominant strategies among flatworms: reciprocal males receive more resources, while hypodermic mated species invest heavily in female organs. Self-fertilization in these species increases with hypodermic mating, suggesting a common evolutionary principle between plants and worms.

Some sperms poison their competitors

Research reveals that sperm cells with the t-haplotype exhibit increased motility and competitiveness, attributed to optimal RAC1 activity. This genetic factor enables them to disable competitors while producing an antidote to protect themselves.

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Rival competition makes ant sperm better swimmers

A study published in BMC Evolutionary Biology found that rival sperm competition makes ant sperm better swimmers, increasing their mobility, speed, and straightness by up to 50%. Researchers discovered that seminal fluid from rival males and queen secretions enhance sperm motility, suggesting a self-non-self-recognition mechanism.

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Rival sperm and choosy eggs

In a groundbreaking study, FSU Professor Don Levitan found that sperm from multiple males compete for fertilization, allowing eggs to choose their preferred mate. This discovery has significant implications for the evolution of reproductive compatibility and the creation of new species.

Forget peacock tails, fruit fly sperm tails are the most extreme ornaments

A new study in Nature found that fruit fly sperm tails are the most extreme ornament, with lengths of up to 6 cm, due to female preference for longer sperm. This preference is linked to genetic correlations between female reproductive tracts and male sperm length, as well as a trade-off between sperm length and number.

Why fruit fly sperm are giant

Researchers found that larger males with more sperm are favored by females, driving the evolution of longer sperm. This study provides the first explanation for the development of giant sperm in fruit flies.

Winter season reverses outcome of fruit fly reproduction

Researchers found that winter hibernation reverses the typical sperm competition outcome in fruit flies. In cold temperatures, only the first male fathered most of the offspring, while subsequent males had little to no success. This discovery could impact pest control strategies and understanding of sperm storage.

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Sperm wars

Evolutionary biologist Steven Ramm explores sperm competition as a key driver of reproductive system evolution, highlighting the diversity of sperm cells and their adaptations to compete for fertilization. This research could inform genetic modification to increase fertility in endangered species.

Testis size matters for genome evolution

Correlation discovered between molecular evolutionary rates and testes weights, suggesting sperm competition fuels genetic variation. Testis size may be key factor in determining genome evolution rates among primate species.

Biologists confirm role of sperm competition in formation of new species

Researchers at Syracuse University's College of Arts and Sciences have confirmed that diversifying sperm competition is a critical step in the formation of new species. The study, published in Current Biology, reveals how postcopulatory sexual selection drives rapid evolutionary changes in ejaculate and female reproductive tract traits.

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'Paranoia' about rivals alters insect mating behavior

Male fruitflies experience a prolonged mating period with females after encountering rival males, increasing the length of mating by up to 93% in some species. This 'paranoid' behavior is thought to ensure fertilization before females mate with other males.

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How much sex is enough?

Research published in BMC Evolutionary Biology shows that polygamous mice produce more fertile offspring due to increased sperm competitiveness. After 12 generations of competitive selection, polygamous males outperformed monogamous males in both paternity and fertility rates.

Owzat! Bushcrickets' big secret revealed

Researchers found Tuberous Bushcricket produces large testes but less sperm per ejaculate, defying traditional thinking. The study suggests males use larger testes to mate repeatedly without exhausting their sperm reserves.

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The more promiscuous the female, the speedier the sperm

Promiscuous female African cichlids stimulate males to produce larger and speedier sperm, a strategy to outcompete rival suitors for reproduction. Researchers used computer simulations to show that this evolutionary adaptation occurs after species transition to more promiscuous mating behaviors.

Infidelity produces faster sperm

A study by Uppsala University researchers found that females' promiscuity leads to males producing faster and larger sperms. The competition among sperms influences various characteristics, including size and speed.

Variety is the spice of life: too many males, too little time ...

In polyandrous female Australian painted dragon lizards, sperm from different males compete to fertilize eggs. Females prefer mating with mixed-color pairs of males, suggesting a strategy to ensure genetic diversity. This unique behavior may contribute to the persistence of both male types in the population.

In birds, expecting to mate leads to higher fertilization rates

Researchers found that quail males who learned to associate a stimulus with access to a female were more likely to fertilize eggs, increasing their reproductive success. The findings suggest that learning plays a significant role in reproductive fitness and evolution.

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Sex is thirst-quenching for female beetles

A study by Dr. Martin Edvardsson found that dehydrated female beetles mate more frequently with males to obtain water from their seminal fluid, a strategy that benefits the male by extending the time before fertilization competition resumes. The research sheds new light on the role of 'nuptial gifts' in insect courtship and mating.

Romance, schmomance -- natural selection continues even after sex

A new study suggests that human males have evolved mechanisms to outcompete rivals for fertilization, even after sex. This phenomenon, dubbed 'sperm competition,' can lead to increased sperm count and more aggressive sexual behavior in response to perceived infidelity.

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Rodent sperm work together for better results

In promiscuous rodents, individual sperm work together in groups to increase competitiveness and successfully reach the female egg. This cooperation enables faster and stronger swimming, making them better competitors in fertilization races.

Protein translation in sperm

Researchers discovered that protein translation takes place in sperm prior to fertilization, essential for sperm functions like motility and fertilization. Inhibiting mitochondrial translation machinery leads to decreased sperm motility and fertility rates.

Meaningless sex? Male mounting reduces sexual promiscuity of females

Researchers found that male mounting, even without semen transfer, reduces a hen's tendency to mate with other males and decreases the number of sperm obtained from a new rooster. This behavior helps defend paternity, suggesting copulations without semen transfer have evolutionary significance.

Royal Society study on adaptability of fish to warming oceans

A Royal Society study found that Antarctic fish can compensate for the initial negative impact of elevated temperatures and regain their original performance levels despite being several degrees warmer. The study suggests that rising temperatures do not necessarily have a long-term negative impact on biodiversity.

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