Researchers have discovered that commonly prescribed medications can disrupt sterol biosynthesis in developing brains, potentially affecting neural development and function. The study highlights the need for reevaluating medication safety during pregnancy and early childhood.
A study of 620,000 children found that maternal type 1 diabetes was associated with increased risk for most types of congenital heart defects in offspring. Obesity and overweight were linked to increased risk for complex defects, such as outflow tract obstruction, while decreasing the risk for ventricular septal defects.
A mouse study found that genetics play a role in susceptibility and resistance to prenatal alcohol exposure, with some strains showing teratogenic effects while others resisted, suggesting genetic influence. The study also highlights the importance of considering genetic factors in human FASD research.