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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Tracing brain chemistry across humanity’s family tree

Researchers found that a single amino acid substitution in the ADSL enzyme affects its stability and expression, contributing to modern human differences in behavior. The study suggests that this change may have provided an evolutionary advantage in certain tasks.

SAMSUNG T9 Portable SSD 2TB

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A new Denisovan mandible from Taiwan

Penghu 1, discovered on the seabed of the Penghu Channel in Taiwan, is revealed to be a Denisovan mandible dating back to 10,000 years ago. The fossil's molecular identification sheds light on the mysterious distribution and appearance of Denisovans in eastern Asia.

Researchers reveal dietary diversity of denisovans on Qinghai-Xizang Plateau

Researchers studied over 2,500 bones from the Baishiya Karst Cave and found a diverse range of animal species consumed by Denisovans, including blue sheep, wild yak, equids, and carnivores. The analysis revealed that Denisovans adapted to the harsh environment by processing animal carcasses and extracting resources.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Decoding the three ancestral components of the Japanese people

The research group found that the Japanese population can be divided into three clusters, with different concentrations in Okinawa, Northeastern Japan, and Western Japan. They also identified genetic variants associated with hereditary breast cancer and provided insights into gene sequences derived from Neanderthals and Denisovans.

Were Neanderthals morning people ?

Genetic material from Neanderthal ancestors may have influenced the preference for waking up early in some people. Studies found that introgressed genetic variants from Neanderthals are associated with increased morningness and a shorter circadian period, which is beneficial at higher latitudes.

A climate-orchestrated early human love story

A recent study reveals that past climate changes and vegetation shifts played a key role in determining when and where early human species interbred. The research suggests that the overlap of habitats led to increased encounters and interactions among groups, increasing the chance of interbreeding.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Human ancestry has been shaped by mixing and matching alleles

Recent studies reveal complex patterns of admixture in human populations, particularly in Africa and the Americas. In Africa, ancient introgression from Neanderthals and Denisovans contributed to increased genetic diversity, while in the Americas, modern admixture resulted in redistributed archaic ancestry.

Traces from the past

A team of researchers has developed a non-destructive method to extract DNA from bones and teeth, allowing for direct attribution of cultural objects to specific individuals. The breakthrough enabled the recovery of ancient human DNA from a 20,000-year-old pendant, providing insights into Paleolithic societies.

Apple iPhone 17 Pro

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Study offers new insight on what ancient noses smelled

Scientists recreated ancient human and Denisovan noses to compare their olfactory receptor genes, finding differences in sensitivity to various odors. This research sheds light on how our closest genetic relatives perceived and interacted with their environment.

Immune system of modern Papuans shaped by DNA from ancient Denisovans

A recent study found that Denisovan DNA sequences near immune-related genes in modern Papuans regulate their activity, affecting how people respond to infections. The research suggests that Denisovan DNA contributed to the adaptation of early modern humans living in New Guinea and nearby islands.

Ancient DNA analysis sheds light on the early peopling of South America

Researchers used DNA from two ancient human individuals to unravel the deep demographic history of South America, providing new genetic evidence supporting existing archaeological data. They also discovered migrations along the Atlantic coast for the first time and found evidence of Neanderthal ancestry within ancient genomes.

AmScope B120C-5M Compound Microscope

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Tooth unlocks mystery of Denisovans in Asia

The discovery of a 164,000- to 131,000-year-old Denisovan tooth in Laos provides significant insights into the species' geographic range. The ancient tooth's shape and similarity to teeth found on the Tibetan Plateau suggest that Denisovans inhabited Southeast Asia, particularly northern Laos.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Molecular analysis reveals the oldest denisovan fossils yet

A team of researchers has extracted and analyzed ancient proteins and DNA from nearly 4,000 bone fragments at Denisova Cave, yielding five human bones with intact biomolecules, dating back to 200,000 years ago. The findings provide robust insights into the first occupants of the cave and their archaeological signature.

In a gene tied to growth, scientists see glimmers of human history

Researchers have identified a shortened version of the human growth hormone receptor gene, GHRd3, which may help people survive in situations where resources are scarce or unpredictable. The study found that this variant emerged around 1-2 million years ago and was more prevalent in ancient humans and Neanderthals.

CalDigit TS4 Thunderbolt 4 Dock

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Neandertal and Denisovan blood groups deciphered

Researchers analyzed Neandertal and Denisovan genomes to identify blood groups, confirming their African origin and Eurasian dispersal. The study also found evidence of low genetic diversity and possible demographic fragility, shedding light on the disappearance of Neandertals.

Exploring blood types of Neanderthal and Denisovan individuals

A study analyzing ancient DNA has uncovered new information on the blood types of Neanderthals and Denisovans. The analysis reveals consistent African origins and increased vulnerability to diseases affecting fetuses and newborns, confirming previous evidence of low genetic diversity leading to eventual demise.

Pleistocene sediment DNA from Denisova Cave

The study found that Denisovans produced the oldest stone tools at the site between 250,000 and 170,000 years ago, while Neandertals arrived later. The researchers also detected modern human mitochondrial DNA for the first time, suggesting they brought new technology to the region.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

New evidence in search for the mysterious Denisovans

Researchers found no evidence of interbreeding between modern humans and Denisovans in Island Southeast Asia, but confirmed high levels of Denisovan ancestry in the region. The study suggests that significant genetic exchange occurred between Denisovans and modern humans who arrived in Asia 50,000-60,000 years ago.

Genes for face shape identified

A UCL-led team discovered 32 gene regions affecting facial features such as nose and lip shapes. The analysis of over 6,000 volunteers found that one gene, TBX15, was inherited from the Denisovans, an extinct group of ancient humans.

Denisovan DNA found in sediments of Baishiya Karst Cave on Tibetan Plateau

Researchers discovered Denisovan DNA in sediments from the Baishiya Karst Cave on the Tibetan Plateau, revealing that Denisovans occupied the region for a long time and had adapted to the high-altitude environment. The findings support the idea that Denisovans had a wide geographic distribution beyond Siberia.

Denisovan DNA in the genome of early East Asians

Scientists identify a 34,000-year-old Early East Asian fossil with mixed Eurasian descent, showing a quarter of its ancestry came from western Eurasians. The study found that the individual's DNA contained segments from extinct hominins, including Denisovans and Neandertals.

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New Denisovan DNA expands diversity, history of species

Researchers from Arizona State University have recovered ancient Denisovan mitochondrial DNA from Baishiya Karst Cave on the Tibetan Plateau, dating back to around 100,000 years ago. The discovery suggests that Denisovans may have interbred with modern humans in northeast central Asia, influencing genetic adaptations to high altitude.

Icelandic DNA jigsaw-puzzle brings new knowledge about Neanderthals

Researchers analyzed the genomes of over 27,000 Icelanders to create a new image of Neanderthals, finding that they had children with Denisovans before meeting Homo Sapiens. The study reveals significant fragments of Denisovan genes in Icelandic DNA, challenging previous assumptions about hybridization and genetic transfer.

Modern Melanesians harbor beneficial DNA from archaic hominins

A recent study reveals that modern Melanesians have inherited beneficial genetic variants from archaic Neanderthal and Denisovan hominins. These genes are associated with positive selection in the Melanesian genomes, particularly at chromosomes 16p11.2 and 8p21.3, suggesting an adaptive role in environmental adaptation.

Dishing the dirt on an early man cave

A team of scientists uncovered new details about day-to-day life in the famous Denisova Cave complex in Siberia's Altai Mountains. Microscopic studies of fossil droppings and charcoal from ancient fires indicate that large carnivores such as hyenas, wolves, and bears dominated the landscape for over 300,000 years.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Long lost human relative unveiled

Researchers have reconstructed the skeletal anatomy of Denisovans using DNA methylation patterns, identifying 56 unique features. The study reveals that Denisovans had a wider skull, longer dental arch, and unique traits that separate them from modern humans and Neanderthals.

Extinct human species gave modern humans an immunity boost

A recent study found that modern humans acquired a gene variant from Denisovans that increases immune reactions and protective responses to disease-causing microbes. The Denisovan gene variant, I207L, was discovered in families with severe autoimmune conditions and was also present in an extinct human species found in the Altai Mountains.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Dental evidence of human admixture in Asia

A study found a three-rooted lower molar in a 160,000-year-old Denisovan mandible from China, suggesting that the trait is much older than previously thought. This rare dental feature may have been passed into modern Asian human populations through interbreeding with Denisovans.

Do you hear what I hear?

A new study found that infants at high risk for autism were less able to distinguish between familiar and unfamiliar speech patterns. The researchers suggest that interventions should begin during infancy for those at high risk.

Tibetan plateau first occupied by middle Pleistocene Denisovans

A recent study published in Nature confirms that Denisovans lived on the Tibetan Plateau during the Middle Pleistocene era. The discovery of a 160,000-year-old human mandible found in Xiahe, China, provides evidence of an early human presence on the plateau, predating modern humans.

GoPro HERO13 Black

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First hominins on the Tibetan Plateau were Denisovans

The Xiahe mandible, discovered on the Tibetan Plateau, is at least 160,000 years old and shares anatomical features with Denisovans from Denisova Cave. The ancient proteins found in the mandible indicate a hominin population closely related to Denisovans.

Multiple Denisovan-related ancestries in Papuans

A new study led by Murray Cox has found that modern Papuans carry hundreds of gene variants from two deeply divergent Denisovan lineages, separated for 350,000 years. The research reveals a complex history of interbreeding between modern humans and archaic hominins in Island Southeast Asia.

Ancient DNA reveals new branches of the Denisovan family tree

A new study of ancient DNA fragments in modern Papuans and Islanders suggests two distinct Denisovan lineages separated for hundreds of thousands of years, one potentially a new archaic hominin species. The findings highlight the importance of considering underrepresented regions in genome data to improve scientific interpretations.

New studies reveal deep history of archaic humans in southern Siberia

Archaeologists have dated the archaeological site of Denisova cave to at least 200,000 years ago, with stone tools suggesting human occupation may have begun as early as 300,000 years ago. Neanderthals visited the site between 200,000 and 100,000 years ago, interbreeding with Denisovans around 100,000 years ago.

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Neandertal mother, Denisovan father!

A single bone fragment from Denisova Cave has revealed the genetic makeup of a child born to a Neandertal mother and a Denisovan father. The study's findings suggest that Neandertals and Denisovans interbred frequently, with the child showing ancestry from both groups.

Modern humans interbred with Denisovans twice in history

Researchers discovered two distinct episodes of Denisovan genetic intermixing between modern humans and Denisovans. The genomes of modern Papuan individuals contain approximately 5% Denisovan ancestry, while East Asians have a second set of Denisovan ancestry not found in South Asians and Papuans.

New look at archaic DNA rewrites human evolution story

A University of Utah-led team analyzed archaic DNA to reconstruct the early history of humans, revealing an evolutionary story that challenges traditional views. The study found that Neanderthals and Denisovans nearly went extinct after separating from modern humans, but later diverged and grew into tens of thousands of individuals.

Kestrel 3000 Pocket Weather Meter

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A world map of Neanderthal and Denisovan ancestry in modern humans

A new study maps Neanderthal and Denisovan ancestry in modern humans, revealing previously unknown interbreeding events, especially in South Asians and Oceania populations. The research suggests that Denisovan genes may be linked to a more subtle sense of smell and high-altitude adaptations.

Ancient Denisovan DNA excavated in modern Pacific Islanders

Researchers have excavated substantial genomic remnants of the extinct Denisovans in Oceania populations, shedding light on early human history. The study identified genes inherited from Neanderthals and Denisovans that conferred advantages to the ancestors of modern Island Melanesians.