Articles tagged with Amplicons
A novel circular RNA replicon was identified in a high-temperature hot spring ecosystem, showing profound divergence from previously known circular RNAs. The discovery reveals diverse self-replicating RNAs exist even in extreme environments, broadening the ecological scope of RNA-based replication systems.
A team of researchers uses CRISPR gene editing to eliminate cells with amplified oncogenes, reducing tumour growth and increasing animal survival. The study offers a promising approach for precision therapies in resistant cancers.
Researchers found unique bacteria taxa in normal-weight children vs overweight/obese children, suggesting BPA promotes different microbial communities. Gut microbiota responds differently to BPA exposure depending on BMI.
A new algorithm called Meta-Apo reduces the need for expensive whole-genome sequencing to understand microbial function, improving consistency with 16S rRNA gene amplicon results. This approach enables accurate diagnoses like gingivitis improvement from 65% to 95% using low-cost 16S-amplicon sequencing.
A recent study published in Scientific Reports reveals that shotgun sequencing, a favored method for measuring microbial biodiversity, is not as accurate as once thought. Amplicon sequencing, on the other hand, revealed more than twice the number of phyla and 27% more families in water samples from Brazil's major river floodplain systems.
A new study reveals that amplicon sequencing is more robust than shotgun sequencing in discovering microbial biodiversity, with 27% more families identified. The research has significant repercussions for future analyses of microbial diversity.
A new software tool called Acacia has been developed to correct errors in DNA sequencing, allowing biologists to accurately interpret genetic information. The tool, created by CSIRO PhD student Lauren Bragg, uses statistical theory to analyze code for DNA bases and improve accuracy.