Decoding HIV’s tactics
HIV-1 uses 'hidden gene fragments' called uORFs and iORFs to fine-tune protein production and interact with the host immune system. The virus also manipulates ribosome collisions to prioritize its own needs while stalling host defense mechanisms.
SourceHelmholtz Centre for Infection Research·JournalNature Structural & Molecular Biology·TypeExperimental study·DateJan 16, 2025