Articles tagged with Rnai Screening
In vivo RNAi screening reveals new key players controlling hepatocyte proliferation and regenerative capacity. The study demonstrates increased repopulation efficiency and regenerative capacity in chronically damaged mouse livers after stable knockdown of candidate genes.
A team of researchers at Harvard Medical School used RNAi to systematically knockdown pairs of genes in fruit fly cells, revealing interactions between genes and accelerating the pace of discovery in systems biology. This approach overcomes limitations of traditional single-gene knockout studies by capturing redundant gene functions.
The JAK/STAT signaling pathway is a crucial regulator of cell growth and survival in various organisms. Research at the Cold Spring Harbor Laboratory has shed light on the molecular mechanisms underlying this pathway.