Articles tagged with Sex Chromosomes
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A BSC study analyzed 8,906 patient samples to explore disease connections between women and men. It identified different biological pathways for co-occurring diseases depending on sex, highlighting the need for sex-specific risk-reduction strategies.
A new study published in CANCER found that men are more likely to have advanced disease and high myeloma load at diagnosis compared to women. Men were also less likely to have low bone mineral density and had different chromosomal abnormalities, which may contribute to the sex disparity in multiple myeloma risk.
Scientists have discovered a protein called SCEP3 that ensures even chromosome segregation in plants, preventing infertility and genetic diseases. This finding has implications for plant breeding and understanding human fertility, with the equivalent gene SIX6OS1 potentially playing a role in promoting correct chromosome segregation.
Researchers at UCLA Health have identified a sex-chromosome linked gene that drives inflammation in the female brain, making women more susceptible to conditions like Alzheimer's disease and multiple sclerosis. Deactivating this gene and using diabetes medication metformin showed promising results in reducing symptoms in female mice.
As women age, more genes on their X chromosomes escape silencing, potentially influencing disease. This epigenetic change may explain sex-based differences in age-related diseases.
Researchers found that only a small fraction of proteins have genetic differences between males and females. Instead, lifestyle, education, and access to resources also contribute to the health gaps experienced by men and women.
Researchers discovered that independent evolution of chromosome copies in oribatid mites enables genetic diversity through mechanisms like the Meselson effect and horizontal gene transfer. This approach allows for rapid adaptation to environmental changes and supports long-term survival.
Researchers have reconstructed the evolutionary origin of the complex configuration of multiple sex chromosomes in echidnas using their nearly gapless genome sequence. The high-quality data helped trace genetic events that led to this remarkable chromosomal arrangement, including chromosome fusion and fission events.
A new University of Texas at Arlington study provides a comprehensive genetic map of the common bedbug Cimex lectularius, enhancing scientific investigations into pesticide resistance and developing targeted pest control strategies.
A new study reveals that benzyl butyl phthalate (BBP) causes oxidative stress and DNA strand breaks, leading to cell death and abnormal chromosomes in egg cells. The research suggests that BBP exposure can lead to lower quality egg cells with compromised genomic integrity.
A new study reveals a connection between NF-κB signaling pathways and X chromosome inactivation in T cells, which has implications for understanding sex-based immune responses. Researchers found that the maintenance of X chromosome inactivation depends on nuclear factor kappa B (NF-κB), a transcription factor.
The University of Texas at Arlington has awarded seven Interdisciplinary Research Program (IRP) grants totaling $140,000 to foster collaboration between groups. The grant increase represents a 40% boost over the previous year's funding.
Researchers discovered extreme differences in mitochondrial gene activity between males and females, highlighting the need for sex-specific disease therapies. The study, published in the Proceedings of the National Academy of Sciences, found that male mitochondria exhibit more protein-coding genes than females.
A noncoding gene has been identified as the deciding factor in determining sex in Argentine ants, with a specific genomic region being crucial to this process. The gene does not encode a protein but rather produces an RNA that influences sex determination.
Researchers analyzed over 200 butterfly and moth genomes to understand their evolutionary history. They found that chromosomes have remained largely unchanged since the last common ancestor over 250 million years ago, despite the diversity seen today in wing patterns and caterpillar forms.
Researchers at the Francis Crick Institute have identified the first prehistoric person with mosaic Turner syndrome, characterized by one X chromosome instead of two. The study also found the earliest known incidence of Jacob's syndrome, Klinefelter syndrome, and an infant with Down Syndrome in ancient DNA samples.
A Geisinger Health System study found that individuals with an additional X or Y chromosome have a four to five times higher risk of developing venous thromboembolism, a life-threatening condition. The analysis included data from over 642,000 patients and suggests that identifying those at high risk could minimize unnecessary illness a...
Scientists from BGI Genomics successfully generated a gapless genome assembly for the East Asian finless porpoise, which is approximately 2.5 Gb in size and has 22,814 protein-coding genes. The study provides new resources for comparative genomics of cetaceans and conservation biology of threatened species.
Researchers have discovered a new critical period for sex determination in sea turtle embryos, influenced by temperature fluctuations. The study reveals two peaks in temperature's impact on sex ratio during the thermosensitive period of development.
Researchers from UCLA have developed a strategy to identify novel treatments for cognitive decline and neurodegenerative diseases by exploiting sex differences in the brain. The study provides a roadmap for disentangling the contribution of sex-specific factors, which can yield treatments optimized for each sex.
Researchers have discovered a selfish genetic element, known as Segregation Distorter (SD), that skews genetic inheritance. SD has caused dramatic changes in chromosome organization and genetic diversity, leading to the accumulation of deleterious mutations.
Research on two worm phyla provides clues on how separate sexes originated and evolved in animals. The study characterizes the evolution of sex chromosomes in flatworms and roundworms, revealing that their diversity is a result of different combinations of genetic elements.
Researchers have identified 2,320 sex-heterogeneous SNPs linked to various health traits and diseases, including schizophrenia, type 2 diabetes, and ADHD. These SNPs play a role in early-life biological processes that shape distinct biology and traits between sexes.
Researchers have identified the Xist gene as a critical regulator of fetal development in mice, leading to miscarriage and abnormal placentas when epigenetic instructions are missing. The study's findings suggest that failed Xist imprinting can be 'cured' by targeting specific genes involved in histone modifications.
A team of researchers at George Washington University identified a gene that determines whether ultraviolet iridescence appears in the wings of butterflies. Removing this gene from non-iridescent species leads to UV coloration in their wings, highlighting its critical role in evolutionary differences between species.
Scientists at the Francis Crick Institute have developed a gene-editing method to control the sex of mouse offspring, demonstrating its potential to reduce culling in scientific research and farming. The technology shows 100% efficiency in producing single-sex litters, with minimal impact on litter size.
A study by University of Utah biologists discovered a mutation in the ROR2 gene is linked to short beak length in domestic pigeons. This mutation also underlies the human disorder Robinow syndrome, which shares striking facial features with the pigeon phenotype.
Researchers have discovered that bearded dragon embryos can become females through two distinct pathways: one activated by sex chromosomes and the other by high temperatures during development. Ancient cellular processes are likely involved in temperature-dependent sex reversals.
Scientists discovered six sex chromosomes in the Odorrana swinhoana frog species, revealing insights into how complex XY systems evolve. The finding suggests that translocation, a chromosomal abnormality, may have occurred by chance or been non-randomly selected.
A new review reveals a surprising number of exceptions to the purported rules of sex chromosome evolution, questioning their applicability across species. Global dosage compensation is found to be the exception rather than the rule, and studies show high rates of turnover and diversity in sex chromosomes.
Researchers discovered physically linked mating type loci in 24 Trichosporonales fungi species, with highly conserved gene sequences. This is unusual, as mating type chromosomes tend to degenerate during evolution, and the mechanisms stabilizing these loci will be analyzed in future studies.
Brazilian and German scientists have discovered genes linked to sex differentiation in the giant Amazon fish, enabling early sexing and paving the way for genetic improvement. The research, supported by FAPESP, has significant implications for the Brazilian aquaculture industry and the conservation of this iconic species.
Research by scientists from Cornell University and the University of Sheffield finds that balancing selection is responsible for maintaining the diversity of head colors in Gouldian Finches. This process allows both red- and black-headed finches to coexist, with each having advantages and disadvantages, resulting in a stable polymorphism.
Researchers found gene cassettes transfer across generations in strawberry plants, leading to sex chromosome changes and homomorphic female heterogametic inheritance. The discovery sheds light on the mechanisms behind sex chromosome evolution and has implications for creating new crop varieties.
A new study has identified the earliest stages of evolution where distinct sperm and egg cell types first emerged from a simpler ancestral mating system. The research found that the sex-determining region associated with male-female differentiation in algae is surprisingly small, consisting of only one gene called MID.
Researchers at UC Davis have made significant discoveries about the complex process of meiosis, where chromosomes undergo a intricate dance to produce sperm and eggs. The team found that SUMO and ubiquitin proteins play a crucial role in selecting crossover sites, allowing for accurate chromosome distribution.
Researchers discovered a network of proteins often linked to cancer plays a crucial role in male fertility and the birth of healthy offspring. The study, published in Cell Reports, sheds light on the precise epigenetic regulation of sex chromosomes and their impact on germline cells that produce male sperm.
The Chinese alligator genome has been sequenced, revealing adaptations for living in both water and land habitats and providing insights into the species' unique features. The study also sheds light on temperature-dependent sex determination and immune system development.
Researchers from the University of Pittsburgh have documented early separate-sex evolution in a wild strawberry species still transitioning from hermaphroditism. This finding provides evidence for the theory that males and females developed from hermaphroditic ancestors, with plants serving as models for understanding early evolution.
A new study reveals similarities between DNA that determine mating types in fungi and those that determine sex in plants and animals. This makes fungi an interesting model organism for studying the evolutionary development of sex chromosomes.
A research team proposes that sexual conflict can establish novel sex-determination genes and sex chromosomes, explaining their rapid evolution. The model suggests that genes with sexually antagonistic effects and mutations influencing sex determination are common in nature.
Research finds that female bird species develop a sexual preference for males of their own species, driven by genes on the sex chromosome inherited from the father. This discovery sheds light on how new species are formed and may explain the existence of new species despite occasional hybridization.
Genomic imprinting evolved in a stepwise, adaptive way, with genes becoming imprinted as needed. The study provides important clues about the evolution of imprinting, despite its complex nature.
The study analyzed a dataset of 107 plants and animals, showing that the opportunity for selection to act on a gamete can influence recombination rates. The researchers found that strong selection on female gametes could lead to lower recombination rates in females.
Researchers at Johns Hopkins Medicine verified Down syndrome in a genetically modified mouse model, finding identical skull and facial deformities as seen in humans. The study used sophisticated statistical techniques to match the mice' data with well-established characteristics of DS patients.