A new method called ATTACH identifies strong interactions between T cells and cancer-specific proteins to isolate effective tumor-reactive T cells. This approach overcomes key challenges in immunotherapy development, offering a rapid and accessible way for isolating rare immune cells.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalJournal for ImmunoTherapy of Cancer·DateJul 8, 2026
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers at the Francis Crick Institute have developed a new method to enhance anti-cancer immunity by redirecting non-specialized immune cells to present a broader range of tumor antigens. This approach, leveraging understanding of dendritic cell biology, has shown promise in reducing tumour growth and amplifying responses in mice.
SourceThe Francis Crick Institute·JournalNature Cancer·DateMay 20, 2026
The University of Colorado Anschutz Gates Institute has achieved first-in-U.S. FDA clearance for a novel CAR T-cell therapy targeting aggressive leukemia cells, representing a potential new treatment approach for patients with hard-to-treat disease. The therapy will be evaluated in a Phase 1 clinical trial starting this summer.
Fecal microbiota transplantation (FMT) shows promise in enhancing cancer immunotherapy outcomes, with some studies demonstrating remarkable improvements and others showing no benefit. The success of FMT depends on multiple factors, including donor selection and specific bacterial communities being transferred.
SourceFAR Publishing Limited·JournalGut Microbes·TypeLiterature review·DateJul 30, 2025
A team of researchers has identified a novel oncometabolite that accumulates in tumors and impairs immune cells' ability to fight cancer. The study highlights how the metabolic environment of tumors influences T cell function, opening new possibilities for improving cancer immunotherapy by targeting tumor metabolism.
SourceUniversity of Chicago Medical Center·JournalNature Cell Biology·TypeExperimental study·DateApr 21, 2025
A new study found that CAR-T cell therapy success is predicted by three key features: the CD4/CD8 ratio in infusion products, the presence of T-cell exhaustion signals before infusion, and the expansion of T-cells during therapy. These factors can help improve treatment outcomes.
SourceJosep Carreras Leukaemia Research Institute·JournalCell Reports Medicine·TypeComputational simulation/modeling·DateOct 28, 2024
SAMSUNG T9 Portable SSD 2TB
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A team of Chinese and UK researchers has identified superoxide dismutase 1 (SOD1) as a potential target for reversing drug resistance in ovarian cancer. By using nanoparticles to deliver siRNA that reduces SOD1 levels, the study showed reduced growth and decreased resistance to cisplatin in female mice.
SourceXi'an Jiaotong-Liverpool University·JournalCancer Gene Therapy·TypeExperimental study·DateSep 6, 2023