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Risk allele for side effects induced by Clozapine identified

A significant association has been found between HLA-B*59:01 and Clozapine-induced agranulocytosis and granulocytopenia, suggesting the allele may serve as a marker for prioritizing patients at low risk of developing these severe side effects. Further analysis is needed to clarify the mechanism behind this association.

SourceOsaka University·JournalBiological Psychiatry·DateApr 5, 2016
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