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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

A tug-of-war explains a decades-old question about how bacteria swim

Bacteria move through liquids using propellerlike tails called flagella, which alternate between clockwise and counterclockwise rotation. Researchers propose a tug-of-war mechanism instead of the traditional equilibrium 'domino effect' model, where proteins lining the tail exert pressure on their neighbors.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Gut bioelectricity provides a path for bad bacteria to cause diseases

A team of researchers at UC Davis Health discovered a novel bioelectrical mechanism that allows Salmonella bacteria to navigate the gut lining and find vulnerable entry points. The study found that Salmonella bacteria detect electric signals in FAE, which helps them move towards openings in the gut where they can enter.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Run (and tumble) to dinner

Scientists from the Institute of Industrial Science have developed a theoretical model for optimal search strategy in biological systems, which may help design new drones or nanobots. The model uses stochastic optimal control theory to analyze chemotaxis, a process of attraction to chemical gradients.

Bacteria navigate on surfaces using a 'sense of touch'

Researchers found that Pseudomonas bacteria use a network of proteins to regulate twitching and respond to mechanical forces, allowing them to navigate based on what they feel in front of them. This 'sense of touch' helps the microbes move forward in the same direction when moving as a group.

E. Coli calculus: Bacteria find the derivative optimally

Researchers from The University of Tokyo have shown that the standard model biologists use to describe bacterial chemotaxis is mathematically equivalent to optimal dynamics. By using nonlinear filtering theory, they found that the system used by bacteria is indeed optimal for efficient sensing and adaptation in noisy environments.

Modelling speed-ups in nutrient-seeking bacteria

Researchers developed a more accurate model of how bacteria search for nutrients by considering both chemotaxis and chemokinesis. The new model reveals that combining these two motions enhances population responses to nutrient distributions.

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Autonomous microtrap for pathogens

Scientists have developed a self-propelled chemical trap to corner and destroy pathogens in body fluids, reducing the need for antibiotics. The device uses a magnesium metal engine propelled by hydrogen bubbles, trapping bacteria with an acid-soluble polymer cage that releases a toxin to kill them.

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Actively swimming gold nanoparticles

Scientists have designed gold nanoparticles to mimic bacterial swarming behavior, creating a collective movement towards glucose gradients. The artificially created nanoswimmers exhibit chemotactic behavior, similar to bacteria, and demonstrate the potential for studying collective intelligence on the nanoscale.

'Curvy bacteria' weigh the benefits of different shapes

Researchers found that curved shapes can facilitate efficient swimming and chemotaxis, but come with higher cell construction costs. This discovery opens questions about the shape of disease-causing bacteria and its potential industrial applications.

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Bacteria change behavior to tackle tiny obstacle course

Researchers discovered E. coli bacteria change behavior to navigate tiny obstacle courses, defying predictions of slowing progress. The study's findings have implications for biology, medicine, and robotic search-and-rescue tactics.

Bacteria reveal strong individuality when navigating a maze

Researchers at ETH Zurich discovered that bacteria in a microfluidic T-maze exhibit diverse chemotactic sensitivity due to genetic variations, allowing some individuals to outperform others. This phenotypic heterogeneity may provide an evolutionary advantage for the bacteria, enabling them to adapt to changing environments.

Incentive to move

Researchers have identified the structure of a central protein used by archaea to determine direction, revealing significant differences from bacteria. This discovery sheds light on how archaea can adapt to extreme environments and colonize new habitats.

Overcoming the last line of antibiotic resistance against bacterial infections

Staphylococcus aureus, a common bacteria causing severe infections, has developed mechanisms to evade the human immune system. Researchers have identified various tactics used by S. aureus to slow down neutrophil migration, impede priming, and even kill neutrophils. Understanding these strategies can lead to new therapeutic approaches.

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How Vibrio cholerae is attracted by bile revealed

Researchers discovered Vibrio cholerae attraction to bile taurine, shedding light on its survival and pathogenicity. The finding may lead to prevention of infection and development of new drugs for cholera.

Beneficial bacteria in Hawaiian squid attracted to fatty acids

Researchers have discovered a novel receptor in Vibrio fischeri that senses fatty acids, allowing the bacterium to migrate towards these compounds. This finding sheds light on the symbiotic relationship between the Hawaiian bobtail squid and its luminescent bacteria.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Ulcer-causing bacteria tamed by defect in cell-targeting ability

Researchers have discovered a defect in the cell-targeting ability of Helicobacter pylori bacteria that leads to reduced inflammation in the stomach. The study found that the bacteria's chemotaxis, or movement towards specific chemicals, plays a crucial role in triggering chronic inflammation.

Microbial study reveals sophisticated sensory response

A new study demonstrates that even a simple microbe can achieve sophisticated sensory adaptation, allowing its behavior to remain consistent in ever-changing background conditions. Researchers found that E. coli responds to relative changes in sensory inputs rather than absolute concentrations.

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American Society for Microbiology honors Caroline S. Harwood

Harwood's discovery of the genes and enzymes involved in lignin degradation has major implications for environmental pollution and carbon cycling. Her work on light-driven nitrogenase processes also holds promise for sustainable energy production.

Spontaneous assembly

A team of scientists used PALM microscopy to show that bacterial membrane proteins can spontaneously form clusters without being actively distributed. The researchers found that random lateral protein diffusion and protein-protein interactions generate complex, ordered patterns in the chemotaxis network.

Predatory bacterial swarm uses rippling motion to reach prey

Researchers discovered that Myxococcus xanthus uses a rippling motion to hunt other bacteria, with the pattern adapting to prey density. The study found that individual cells line up and move in an alternating pattern, producing high and low cell density waves.

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Marine bacteria's mealtime dash is a swimming success

Researchers at MIT demonstrated that marine bacteria, specifically P. haloplanktis, use their rapid swimming abilities to locate and exploit tiny nutrient patches in the ocean. This behavior has global implications for the oceans' health during climate change and could impact the carbon cycle.

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