Articles tagged with Streptomyces
Researchers developed FAST-NPS, a new automated method to discover and scale up bioactive natural products from Streptomyces. The method uses self-resistance genes as markers to prioritize biosynthetic gene clusters with bioactivity.
Researchers have discovered two Antarctic actinomycete strains with strong antifungal properties against the fungus causing banana wilt. The strains, Streptomyces polyrhachis and Streptomyces fildesensis, showed effective inhibition of Fusarium oxysporum growth, making them potential biocontrol agents for sustainable disease management.
Researchers discovered that Streptomyces davawensis produces virus-like particles facilitating host reproduction. The particles contain an enzyme degrading genomic DNA, allowing for extracellular DNA release and scaffold creation. This finding reveals the exploitation mechanism of virus-related nanoparticles for bacterial proliferation.
Researchers discovered that Streptomyces bacteria produce chemical substances called arginoketides, which trigger biofilm formation, algae aggregates, and fungal signalling. These findings shed light on microbial communication and its impact on soil ecosystems and plant diseases.
Bacteria have found a way to survive stressful environments by producing microscopic syringes called Streptomyces phage tail-like particles (SLPs) that are located inside the cell. These SLPs interact with cellular systems involved in cell wall synthesis and protein translation, providing resistance against osmotic stress.
Researchers at Lawrence Berkeley Lab have found a way to generate an alternative jet fuel by harvesting an unusual carbon molecule produced by soil-dwelling bacteria. The fuel, which works similarly to biodiesel, has the potential to be powerful enough to send a rocket into space.
Researchers developed a combined approach to amplify the large-scale biosynthetic gene cluster, resulting in a 9.59-fold increase in bleomycin production. The method uses a ZouA-dependent DNA amplification system and double-reporters-guided recombinant selection.
Researchers at Washington University in St. Louis used comparative metabologenomics to study the genomes of Streptomyces bacteria and identify key factors that influence drug production. The study found that fine-tuning of specific nucleotides can control antibiotic production, offering new insights for next-generation drug discovery.
A new study reveals the critical role of c-di-GMP in controlling the transition from vegetative growth to sporulation in Streptomyces bacteria. The signaling molecule binds to master repressor BldD, controlling gene activity and ultimately preventing reproductive hyphae from differentiating into spores.
Recent research found that melanin-producing Streptomyces are better at colonizing plants, offering protection against harmful chemicals and pests. The ability to produce melanin helps microbes survive inside plants.
Researchers used time-lapse microscopy to reveal a key protein's role as a 'brake' controlling sporulation timing in Streptomyces. The study found that removing this brake leads to premature sporulation, highlighting the importance of BldC protein binding on the chromosome.
A team of researchers from Ruhr-University Bochum has discovered that the bacterium Streptomyces chartreusis produces 1,044 different substances, exceeding expectations. Many of these substances have pharmaceutical potential and could lead to new treatments for patients who suffer from iron overdose or aluminium toxicity.
French researchers have discovered that Streptomyces bacteria can be used as an environmentally friendly alternative to pesticides. The bacteria promotes plant growth and controls pests in the soil. This study could lead to sustainable agricultural practices and reduce harm to human health and the environment.
A new analysis of a group of bacteria called Streptomyces reveals the way some strains developed advanced abilities to tear up cellulose and points out more efficient ways to make fuel from plant material. The study identifies important enzymes and new groups of enzymes produced when Streptomyces flex particular genes.
Researchers identified a unique interaction between cyclic-di-GMP and protein BldD, which controls the developmental switch in Streptomyces, turning it into an antibiotic factory. The small molecule assembles into a molecular glue, connecting two copies of BldD to regulate development.
Researchers have identified a self-resistance mechanism in Streptomyces platensis bacteria that can bypass antibiotic fatty acid synthesis inhibition. This discovery could lead to the development of new, potent antibiotic drug candidates.
Scientists developed a novel method to identify microbes producing large amounts of bio-oil, which can replace crops in fuel production. This technique could speed up the discovery of new biofuel sources, such as Streptomyces bacteria.
A group of researchers at Brown University has discovered how Streptomyces bacteria regulate genes to break down lignin, a highly stable polymer. The study sheds light on the molecular mechanisms behind lignin degradation and its potential applications in biotechnology.
Researchers have identified a system for targeted amplification of gene clusters in bacteria, which can significantly increase the production of antibiotics. This discovery has the potential to revolutionize the commercial production of antibiotics and may also uncover new, undiscovered antibiotics.
Scientists used genome mining to discover a novel antibiotic in Streptomyces coelicolor, effective against several bacterial strains. The approach also unlocks potential for discovering new antimicrobials and antitumor agents from other micro-organisms.
Scientists at the University of Warwick have found a novel signalling molecule that could stimulate hundreds of new antibiotic pathways in up to 50% of Streptomyces bacteria. The discovery was made using NMR technology and genome mining, and has potential to unlock new antibiotics to combat growing bacterial resistance.