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The evolution of low-temperature adapted enzymes

Researchers used ancestral sequence reconstruction to study the evolution of enzyme thermostability and cold adaptation. They identified key amino acid substitutions that enhanced catalytic activity at low temperatures, revealing a structural shift between intermediate ancestral enzymes.

SourceWaseda University·JournalProtein Science·TypeExperimental study·DateMar 25, 2025

Montana State research team publishes paradigm-challenging discovery in a Yellowstone thermophile

A Montana State University research team, led by graduate student Lisa Keller, has published a groundbreaking paper on how certain bacteria thrive in extreme environments. The discovery challenges current understanding of microbial survival and sheds light on ancient lifeforms' adaptation to Earth's progressive oxygenation.

SourceMontana State University·JournalNature Communications·TypeExperimental study·DateMar 4, 2025

A new bacterial species from a hydrothermal vent throws light on their evolution

A new bacterial species, Hydrogenimonas cancrithermarum, discovered at a deep-sea hydrothermal vent site provides insights into bacterial evolution. The strain represents the first mesophilic sulfur-oxidizing bacterium in its genus, expanding physiological and metabolic characteristics.

SourceHokkaido University·JournalINTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY·TypeExperimental study·DateNov 29, 2023

Vitamin boosts essential synthetic chemistry

Researchers at Rice University have developed a novel method for producing olefins, or alkenes, using vitamin B12 and blue light, eliminating harsh chemicals typically needed in the process. This breakthrough could lead to more efficient and sustainable production of drugs, agrochemicals, and plastics.

SourceRice University·JournalChemical Science·DateDec 8, 2020

Novel potent antimicrobial from thermophilic bacterium

Researchers have discovered a novel glycocin, a small antimicrobial peptide with a sugar group attached, produced by the thermophilic bacterium Aeribacillus palladius. The compound has been successfully expressed in E. coli bacteria, making it easier to produce and investigate. This breakthrough could lead to new alternatives for biofu...

SourceUniversity of Groningen·JournalNature Communications·DateMar 12, 2019

Double the stress slows down evolution

Bacteria adapt more slowly and less efficiently when exposed to two stress factors, leading to smaller population sizes. This affects the evolution of antibiotic resistance, as bacteria are less able to protect themselves from predators, resulting in a stronger influence on their survival rate.

SourceMax-Planck-Gesellschaft·JournalNature Ecology & Evolution·DateDec 7, 2018

Rare proteins collapse earlier

A team of researchers led by Paola Picotti found that only a small fraction of key proteins denature at high temperatures, contradicting previous assumptions. This discovery has implications for understanding protein stability and potentially improving the performance of heat-resistant bacteria for industrial processes.

SourceETH Zurich·JournalScience·DateFeb 28, 2017

Nano power grids between bacteria

Researchers have found nano-wire connections between thermophilic AOM consortia, enabling energy transfer between archaea and sulphate reducers. These direct power wires facilitate the growth of sulphate reducers, providing insight into the anaerobic oxidation of methane.

SourceMax-Planck-Gesellschaft·JournalNature·DateOct 21, 2015

Evolution writ small

Researchers at Rice University studied bacteria in a competition for evolutionary dominance, finding specific genetic mutations that imparted physical advantages. These mutations were linked to increased resistance to temperature changes and protein misfolding, which may be related to human diseases like Alzheimer's.

SourceRice University·JournalMolecular Systems Biology·DateAug 25, 2010

Genomics reveals mechanism of heat resistance in bacteria

Researchers discovered that thermophilic bacteria have an abundance of disulfide bonds, which improve protein stability and boost heat-tolerance. The study identified a specific protein, protein disulfide oxidoreductase (PDO), playing a key role in forming these bonds.

SourcePLOS·JournalPLOS Biology·DateAug 22, 2005

Deep thinking: Scientists sequence a cold-loving marine microbe

Researchers discover key biochemical tools that cold-adapted bacteria use to survive in subzero temperatures, including cell membranes packed with polyunsaturated fatty acids and protective solutes inside cells. The study also reveals potential industrial applications for cold-hardy enzymes found in the Colwellia psychrerythraea genome.

SourceThe Institute for Genomic Research·JournalProceedings of the National Academy of Sciences·DateJul 25, 2005