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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Extreme engineering: Unlocking design secrets of deep-sea microbes

Researchers at Emory University uncover how deep-sea microbes create complex structures through a simple process, driving chaperone-free polymerization of archaeal cannulae. This discovery sheds light on the unique adaptations of extremophiles, which thrive in extreme environments.

Montana State scientists explore mechanics of Yellowstone beetles

A team of researchers, including Bob Peterson and Chelsea Heveran, studied the unique adaptations of tiger beetles living in hot springs to survive high temperatures. The study found that these insects have evolved different abdominal plates to reflect more heat than their counterparts in cooler areas.

The evolution of low-temperature adapted enzymes

Researchers used ancestral sequence reconstruction to study the evolution of enzyme thermostability and cold adaptation. They identified key amino acid substitutions that enhanced catalytic activity at low temperatures, revealing a structural shift between intermediate ancestral enzymes.

SAMSUNG T9 Portable SSD 2TB

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Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

City microbes surviving on disinfectants, research reveals

A new study has identified novel strains of microbes that have adapted to use limited resources in cities, including those found in Hong Kong's subways and skin. These microbes can metabolize manufactured products, posing health risks if they are pathogenic.

Heat-loving marine bacteria can help detoxify asbestos

Researchers have discovered that extremophilic bacteria from high-temperature marine environments can be used to remove iron, silicon, and magnesium from asbestos minerals, reducing their toxicity. This finding has the potential to develop new methods for detoxifying and reusing asbestos as a secondary raw material.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Unwinding the world’s smallest biological rotary motor by degrees

Scientists studied F1-ATPase function in bacteria to clarify the angle of rotation during ATP hydrolysis. The study revealed three sets of short and long dwells associated with different intervals per revolution, resolving a long-term debate over the ATP-cleavage shaft angle.

Going to extremes to tackle oil contamination

Researchers at KAUST have identified thermophilic bacteria with potential to degrade oil contamination. The study reveals that certain bacteria can secrete surfactants and absorb emulsified petroleum into their cells for degradation via enzymatic activity.

Turning up the heat to unlock Cas13's potential

A heat-loving bacterium's Cas13 protein enables specific detection of SARS-CoV-2 and other viruses in a one-pot assay. The technology has been patented and clinically validated, with the aim of mass production and commercialization.

Trust your gut: how your gut microbiota can save you from cancer

A recent review highlights the effects of different intestinal bacteria on colorectal cancer, exploring new therapies for disease prevention and treatment. Beneficial probiotics, such as Akkermansia muciniphila and Lactobacillus rhamnosus GG, exhibit anticancer properties and reduce CRC cell proliferation.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Vitamin boosts essential synthetic chemistry

Researchers at Rice University have developed a novel method for producing olefins, or alkenes, using vitamin B12 and blue light, eliminating harsh chemicals typically needed in the process. This breakthrough could lead to more efficient and sustainable production of drugs, agrochemicals, and plastics.

Division of labor on the surface of bacteria

Researchers at Goethe University Frankfurt and the University of Exeter have found that Thermus thermophilus bacteria possess two types of tiny surface hairs, or pili, with different functions. The thick pili are used for DNA capture, while the thin pili facilitate movement on surfaces.

Structure of protein nano turbine revealed

Researchers have determined the first atomic structure of the V/A-ATPase family, a key energy machine in cells. The enzyme's structure reveals a turbine-like structure with two or three peripheral stalks and additional connecting protein subunits, enabling greater plasticity and flexibility in its rotation mechanism.

Bacteria may travel thousands of miles through the air globally

Researchers propose the 'air bridge' hypothesis, suggesting bacteria can be transported globally through the air, sharing antibiotic resistance genes. Studies collected from hot springs worldwide found identical viral DNA memories in bacteria from distant locations.

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Novel potent antimicrobial from thermophilic bacterium

Researchers have discovered a novel glycocin, a small antimicrobial peptide with a sugar group attached, produced by the thermophilic bacterium Aeribacillus palladius. The compound has been successfully expressed in E. coli bacteria, making it easier to produce and investigate. This breakthrough could lead to new alternatives for biofu...

Double the stress slows down evolution

Bacteria adapt more slowly and less efficiently when exposed to two stress factors, leading to smaller population sizes. This affects the evolution of antibiotic resistance, as bacteria are less able to protect themselves from predators, resulting in a stronger influence on their survival rate.

Rare proteins collapse earlier

A team of researchers led by Paola Picotti found that only a small fraction of key proteins denature at high temperatures, contradicting previous assumptions. This discovery has implications for understanding protein stability and potentially improving the performance of heat-resistant bacteria for industrial processes.

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Beneficial bacteria may protect breasts from cancer

Research suggests that beneficial bacteria like Lactobacillus and Streptococcus may protect women from breast cancer by inducing anticarcinogenic properties. Probiotics could be a potential tool to boost these beneficial bacteria, potentially lowering the risk of breast cancer.

Nano power grids between bacteria

Researchers have found nano-wire connections between thermophilic AOM consortia, enabling energy transfer between archaea and sulphate reducers. These direct power wires facilitate the growth of sulphate reducers, providing insight into the anaerobic oxidation of methane.

Bacterial genome scalpel can identify key gene regions

Researchers at North Carolina State University developed a precision scalpel to excise target genomic regions, revealing essential and non-essential genes. The CRISPR-Cas system enables targeted editing of DNA sequences, allowing for the identification of core genomic regions critical for bacterial survival.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Hot on the trail of metabolic diseases and resistance to antibiotics

Researchers have successfully decoded the atomic structure of the TM287/288 ABC transporter, a heterodimeric protein involved in antibiotic resistance and metabolic disorders. This breakthrough could lead to the development of new treatments against multi-resistant bacteria and tumors.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Evolution writ small

Researchers at Rice University studied bacteria in a competition for evolutionary dominance, finding specific genetic mutations that imparted physical advantages. These mutations were linked to increased resistance to temperature changes and protein misfolding, which may be related to human diseases like Alzheimer's.

U of C alumnus finds high numbers of heat-loving bacteria in cold Arctic Ocean

A team of scientists led by U of C grad Casey Hubert detected high numbers of thermophilic bacteria in subzero sediments in the Arctic Ocean. The bacteria may provide a unique opportunity to trace seepages of fluids from hot sub-seafloor habitats and potentially point towards undiscovered offshore petroleum reservoirs.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Compost heap bacteria could provide 10 percent of UK transport fuel needs

Researchers have developed a new strain of bacteria that can convert waste plant fibre into ethanol, providing a potential solution to the UK's transport fuel needs. The process is energy-efficient and uses agricultural waste materials, offering greater environmental benefits than traditional biofuels.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Shotgun sequencing finds nanoorganisms

Researchers at UC Berkeley used shotgun sequencing to identify new microbes living in mine slime, including three previously unknown Archaea that are the smallest organisms ever found. These nanoorganisms have the potential to thrive on other planets, such as Mars.

Researchers find ways heat-loving microbes create energy

A study by Washington University researchers reveals that heat-loving microbes create energy through various reactions, including the use of sulfur and hydrogen. The findings hold clues to the origin of life on Earth, suggesting a high-temperature environment as the likely last common ancestor.

Genomics reveals mechanism of heat resistance in bacteria

Researchers discovered that thermophilic bacteria have an abundance of disulfide bonds, which improve protein stability and boost heat-tolerance. The study identified a specific protein, protein disulfide oxidoreductase (PDO), playing a key role in forming these bonds.

Deep thinking: Scientists sequence a cold-loving marine microbe

Researchers discover key biochemical tools that cold-adapted bacteria use to survive in subzero temperatures, including cell membranes packed with polyunsaturated fatty acids and protective solutes inside cells. The study also reveals potential industrial applications for cold-hardy enzymes found in the Colwellia psychrerythraea genome.

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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Biologist's find alters the bacteria family tree

Blank's research challenges initial findings on cyanobacteria age, pinning emergence to 2.3 billion years ago using genetic analysis. This breakthrough also sheds light on eukaryote evolution and the development of mitochondria.

Newly Discovered Bacteria Produce Magnetic Material

Researchers have discovered a new type of bacteria that can produce magnetic iron oxides, which could be used to remove heavy metals from contaminated soils and groundwater. The bacteria were found in deep subsurface formations heated by compression and burial, and show potential for bioremediation applications.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.