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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Why oxytocin treatments for social behavior are inconsistent

A study by Steve Chang explores how oxytocin influences brain activity to shape social behavior in rhesus monkeys. The researchers found that oxytocin increased activity in the basolateral amygdala and anterior cingulate cortex when monkeys were socially motivated, maintaining beneficial decisions and social task behavior.

Study unlocks how diabetes distorts memory and reward processing

A new study by UNLV researchers finds that diabetes weakens the anterior cingulate cortex, suppressing reward perception and memory signals, leading to mild cognitive impairment. The connection between high blood sugar levels and Alzheimer's disease may be linked to altered hippocampal theta synchrony.

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Type 2 diabetes may suppress reward

A rat study found that type 2 diabetes can suppress the activity of the anterior cingulate cortex, a region critical for cognition and emotions. This weakening affects reward signals and leads to altered behavior, highlighting a potential link between T2D and psychiatric disorders.

How the brain distinguishes between pain and itch

Researchers discovered distinct neuronal populations in the ACC process pain and itch information separately, with stimulus-specific neurons receiving differentiated synaptic inputs from the mediodorsal thalamus. Suppressing these neurons reduced corresponding sensations without affecting the other.

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Neuroscientists discover how the brain slows anxious breathing

Researchers at the Salk Institute identified a specific brain circuit responsible for slowing anxious breathing, connecting the frontal cortex to the brainstem. This discovery may offer a scientific explanation for the beneficial effects of practices like yoga and mindfulness on alleviating negative emotions and could lead to the devel...

Good timing: UNLV study unravels how our brains track time

The UNLV study found that brain activity patterns change with the number of experiences, not time, and that increasing speed affects perception. The research suggests that our brains register a 'vibe' about time, making it faster when we're having fun or doing tasks efficiently.

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Serotonin booster leads to increased functional brain connectivity

A new study found that the serotonin booster prucalopride increased functional brain connectivity in healthy adults, particularly between cognitive networks. The results suggest that prucalopride may improve cognitive function and have therapeutic potential for depression patients.

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When a task adds more steps, this circuit helps you notice

A new study by neuroscientists at MIT's Picower Institute finds that the anterior cingulate cortex (ACC) and motor cortex collaborate to update understanding and behavior when a task requires more steps. The ACC helps M2 adjust to new rules, but reduced activity leads to increased negative outcome encoding cells' activity in M2.

The brain employs an alarm system to suppress intrusive thoughts

The brain detects unwanted memories and proactively inhibits them using the anterior cingulate cortex (ACC). If inhibition fails, the ACC triggers a reactive alarm to alert other regions to stop the intrusion. This study sheds light on the neural mechanisms of controlling intrusive thoughts.

Pain differs: Researchers unveil distinct neural circuits

A study published in Nature Neuroscience reveals the discrete thalamocortical circuits underlying chronic pain and depressive symptoms. The researchers found that a specific pathway from the parafascicular thalamic nucleus to the anterior cingulate cortex mediates depression-associated pain sensitization.

Rats exchange information about danger in a reciprocal fashion

In a groundbreaking study, researchers found that rats can transfer information about danger to each other in both directions, influencing their responses to threats. The study suggests that this reciprocal exchange of information could enhance the detection of danger within groups, similar to cross-species eavesdropping.

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Seeing disfigured faces prompts negative brain and behavior responses

A new study from Penn Medicine researchers found that people have implicit negative biases against individuals with scars, birthmarks, and other facial differences. These biases are present even when participants are not consciously aware of them, and they can affect neural responses in the brain, leading to reduced empathy.

Where the brain turns quality and quantity into value

Researchers pinpointed the anterior cingulate cortex as the brain region responsible for integrating disparate information to inform 'on-the-fly' decision-making. Activity in this region was associated with combining quality and quantity, while other areas linked to interaction between these factors were also activated.

Brain stimulation and connectivity in mice

Researchers used laser stimulation to increase oligodendrocyte proliferation and alter myelination in the mouse brain, highlighting potential mechanisms underlying brain stimulation and connectivity. These findings suggest a new avenue for exploring the neural basis of brain stimulation therapies.

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Researchers map brain activity to improve prosthetic design

Researchers at the University of Houston have developed a new way to understand how the brain controls walking in complex environments. Using brain-body imaging and motion capture technology, they identified specific areas of the brain involved in locomotion, including the posterior parietal lobe and sensorimotor cortex.

Mice feel others' pain -- literally

A study found that mice exhibit hyperalgesia when housed with withdrawal mice, and inhibiting a specific brain region reverses this effect. The findings suggest a neural overlap between physically-induced and socially-transferred hyperalgesia.

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Heavy alcohol use changes adolescents' brain

A recent study found that heavy alcohol use during adolescence is associated with reduced grey matter volumes, particularly in the anterior cingulate cortex. This can disrupt normal brain maturation, leading to potential long-term effects on impulse control and substance use disorder risk.

Perceived obesity causes lower body satisfaction for women than men

A study by University of York psychologists found that perceiving oneself as obese triggers lower body satisfaction in females compared to males. Brain activity monitoring revealed a link between body perception and emotional processes, shedding light on eating disorder vulnerabilities.

Scientists find the brain's generosity center

Researchers discovered that a specific brain area, the subgenual anterior cingulate cortex, is active when learning to help others. People with higher empathy levels showed increased activity in this region and learned to benefit others faster.

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A 'cingular' strategy for attack and defense

The study found that two specific brain regions, the posterior cingulate cortex and rostral anterior cingulate cortex, are activated when making defensive or offensive strategies. This suggests that intuition plays a key role in rapid strategic decisions, rather than deliberate reasoning.

The rest of the brain gets in the way

A study using fMRI scans found that unnecessary brain activity hinders learning, while reduced neural connections facilitate faster skill acquisition. The researchers' novel analysis methods revealed complex brain networks and community structures that correlate with individual differences in learning rates.

The brain game

Researchers found that quicker learners use different brain regions and have more interconnected networks, while slower learners rely on more individualized brain activity. The study provides insight into the neural mechanisms behind skill learning and practice.

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Resting-state functional connection during low back pain

A study published in Neural Regeneration Research found that experimental low back pain altered the functional connections between the insula and default mode network, affecting regions involved in cognition and emotion. The findings suggest a crucial role of these brain regions in pain processing.

Political views are reflected in brain structure

A new report links differences in brain structure to political orientation, finding that liberals have larger anterior cingulate cortexes and are better at coping with conflicting information, while conservatives have larger amygdalas and are more sensitive to threats.

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Is there a seat of wisdom in the brain?

Researchers at UC San Diego School of Medicine have reviewed the neurobiology of wisdom, identifying key brain regions involved in its attributes such as empathy, compassion and emotional stability. The study suggests an optimal balance between primitive and pre-frontal cortex brain regions may enhance wisdom.

Research suggests why scratching is so relieving

A study using functional MRI technology reveals that areas of the brain associated with unpleasant emotions and memories become less active during scratching, suggesting a possible explanation for its relieving effect. The findings may lead to new treatments for chronic itch, which affects over 30 million Americans.

Scientists gain new understanding of age-related depression and dementia

Researchers found that people with smaller anterior cingulate cortex had higher levels of stress hormones, suggesting a potential cause-and-effect relationship. The discovery deepens understanding of ageing, depression, and Alzheimer's diseases, and may lead to treatments targeting reduced stress hormone levels.

Scientists uncover how brain retrieves and stores older memories

Researchers have discovered that the anterior cingulate cortex plays a crucial role in storing and retrieving lifelong memories. The study, led by Dr. Paul Frankland, found that older memories are transferred from the hippocampus to the cortex over several weeks, likely during sleep.

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