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New discovery rewrites the rules of antigen presentation

A team of scientists has challenged long-held assumptions about how immune recognition works, discovering that lipid molecules can be displayed to T cells in a sideways orientation. This new model allows for more flexibility in the immune system's ability to survey its environment and respond to threats.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Neoself-antigens induce autoimmunity in lupus

Researchers found that neoself-antigens, presented on MHC-II, induce an immune response and lead to autoimmunity in lupus patients. EBV reactivation increases the presentation of these antigens, triggering T cell activation and autoimmune disease development.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Dissecting the genetic factors involved in systemic lupus erythematosus development

A recent study has elucidated the genetic factors involved in systemic lupus erythematosus (SLE) development. The researchers found that HLA-DRB1*15:01 is primarily associated with SLE development in the Japanese population, suggesting its role in influencing disease progression. Furthermore, the study highlights the importance of anal...

Alveolar macrophages help CD8+ T cells go (anti-)viral

Researchers from Nara Institute of Science and Technology found that alveolar macrophages act as antigen-presenting cells to prime CD8+ T cell expansion in the lungs. This process involves the production of interleukin 18, leading to the development of resident memory-type cell populations.