Articles tagged with Central Amygdala
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study published in Science Advances reveals that an autism-linked mutation disrupts brain circuits responsible for erasing fear memories, leading to PTSD-like symptoms. By reactivating specific neurons, researchers were able to reverse the behavioral and physiological abnormalities.
Researchers discovered that activating NPBWR1 neurons in the central nucleus of the amygdala enhances social interactions with novel individuals. This study also found that overexpressing the human NPBWR1 gene in mouse neurons reduces sociability, highlighting the importance of genetic variations in personality traits.
Researchers have discovered that the amygdala uses specialized neurons to learn about threats and rewards, a finding that could lead to more effective treatments for anxiety and drug addiction. By studying how these neurons respond differently to various stimuli, scientists have gained insights into the brain's reward system.
Researchers found that suspected amygdala neurons producing corticotropin-releasing factor are not necessary for alcohol withdrawal or dependence. Instead, the CRF is believed to come from other neurons in the brain, with potential implications for human treatment options.
A new study by the University of Arizona has identified a brain region and neural circuitry that mediate satiation, making it possible to create treatments with fewer side effects for eating disorders and weight management. The parasubthalamic nucleus plays a key role in regulating feelings of fullness after eating.
A study published in Science Advances reveals a previously unknown mechanism behind compulsive alcohol use, which may be targeted by medication. A small group of nerve cells in the central amygdala promote alcohol use despite negative consequences.
A recent study found that neuronal microcircuits in the amygdala play a crucial role in regulating fear responses and suppressing fear memories. The researchers' findings suggest that dysfunction of this system can contribute to anxiety disorders, paving the way for more effective therapies.
New research reveals a strong correlation between opioid use, brain inflammation, and negative emotional states during withdrawal. The study found that inflammation in the gut and central amygdala may contribute to the severity of withdrawal symptoms.
Researchers at Cold Spring Harbor Laboratory have identified a neural circuit in the amygdala that generates anxiety. The critical role of dynorphin was revealed, which could serve as a cellular target for treating anxiety-related disorders.
A new study maps distinct neighborhoods where feelings are assigned to experience in the basolateral amygdala, revealing a region with diverse and dynamic neurons that interact with each other. The findings shed light on how valence assignment works and may provide insights into mental health disorders.
Research in mice reveals that the central amygdala, not the lateral portion, is crucial for aversive learning and associating sensory stimuli with threat. This finding has implications for treating disorders like anxiety and PTSD by modifying fear memories.
Researchers found a circuit in the central amygdala that responds to rewarding events and stimulates reward-related behavior, contradicting the consensus that the structure is primarily linked with fear.
A team of researchers at Cold Spring Harbor Laboratory has identified a new pathway that controls fear memories and behavior in the mouse brain. The discovery, published in Nature, reveals that the paraventricular nucleus of the thalamus plays a critical role in regulating fear learning and memory.
Researchers identified the neurofibromatosis type 1 (Nf1) gene as a key regulator of gamma-aminobutyric acid (GABA), a neurotransmitter that lowers anxiety and increases feelings of relaxation. Variations in the human Nf1 gene are linked to alcohol-dependence risk and severity, suggesting a potential genetic basis for excessive drinking.
Researchers at Cold Spring Harbor Laboratory have identified a novel neural circuit linking the amygdala with the brainstem's fear response center. This discovery sheds light on how fear is translated into behavioral responses, paving the way for potential treatments of anxiety disorders like PTSD.
Researchers have confirmed the importance of the nociceptin system in modulating the effects of stress. The study found that this system can prevent and even reverse some cellular effects of acute stress in an animal model.
A recent study by Cold Spring Harbor Laboratory researchers has identified a specific class of neurons in the central amygdala as crucial for encoding and recalling fear memories. The team used optogenetics to activate these neurons, which release neurotransmitters that enhance or inhibit synaptic connections, leading to fear responses.
A team of Scripps Research scientists found a key biological mechanism underpinning the transition to alcohol dependence. They discovered that neuropeptide Y, a naturally occurring anti-stress agent, plays a crucial role in mediating the transition to alcohol dependence by modulating GABA release in the amygdala.
A Scripps Research study has found that the endocannabinoid system, which regulates memory and emotional reactions, can also dampen the effects of alcohol. The research suggests a potential target for developing drugs to treat alcohol addiction.