Commissures | Topics

Articles tagged with Commissures

A newly discovered signaling molecule helps neurons find their way in the developing brain

Researchers at Rockefeller University discovered a new signaling molecule, NELL2, that guides axons during critical brain development. The molecule directs commissural axons to the midline using Robo3 receptors, shedding light on axon guidance and potential treatments for horizontal gaze palsy with progressive scoliosis.

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Research details how developing neurons sense a chemical cue

Developing neurons use the receptors DCC and neogenin to detect Netrin-1, guiding their growth towards anatomical boundaries. This understanding may lead to the development of drugs for spinal cord or brain injuries.

Chemical gradient steers nerve growth in spinal cord

Researchers discovered a guidance mechanism that regulates nerve cell growth up and down the spinal cord. This discovery may help restore function to people with paralyzing spinal cord injuries by guiding damaged axons towards the brain.