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Simple blood test unveils hidden risks of unstable coronary plaques

Researchers developed a simple blood-based assessment to evaluate high-density lipoprotein's (HDL) cholesterol removal capacity from blood vessel walls. The study linked low HDL function to high-risk coronary plaques, supporting the use of this method for predicting cardiovascular risk.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Researchers achieve the first minimally invasive coronary artery bypass

Researchers at NIH and Emory School of Medicine have successfully performed a minimally invasive coronary artery bypass without cutting the chest wall. The new technique, called ventriculo-coronary transcatheter outward navigation and re-entry (VECTOR), creates a new route for blood flow that is safe from potential blockages.

No support for dual antiplatelet therapy after heart bypass surgery

A study of 2,201 patients after heart bypass surgery showed that dual antiplatelet therapy with ticagrelor and aspirin did not reduce cardiovascular risks but increased the risk of excessive bleeding. The results contradict current guidelines recommending dual therapy for these patients.

How the early heart develops

A team of scientists has found that the ion channel PIEZO2 is crucial for coronary vessel formation and heart development. Without PIEZO2, coronary arteries may develop improperly, leading to oxygen supply issues in the heart muscle. This discovery could lead to earlier diagnosis and treatment of congenital heart defects.

Intestinal bacteria influence aging of blood vessels

Researchers found that intestinal bacteria and their metabolites can accelerate blood vessel aging and trigger cardiovascular disease. The breakdown product of phenylalanine, phenylacetic acid, accumulates with age and leads to senescence of endothelial cells.

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A bypass route for the coronary vessels in the heart?

A novel bypass route for coronary vessels in the heart has been discovered using the VEGF-B growth factor, which can stimulate new blood vessel growth in damaged areas. This finding opens up possibilities for treating myocardial infarction by re-activating embryonic vessel growth programs.

Tiny heart, big promise

Researchers at Children's Hospital Los Angeles identified a new source of cells that can develop into coronary vessels and found the signaling protein CXCL12 guiding this process. The study may have clinical relevance, helping diagnose abnormal coronary vessels and developing interventional strategies to prevent heart attacks.