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The development of mirror-image pain

A study published in Communications Biology found that lysophosphatidic acid (LPA) exacerbates chronic pain and drives mirror-image pain after a stroke. The researchers used imaging mass spectrometry to visualize LPA and other molecules, revealing a sequential pathological process that leads to bilateral pain.

SourceKyoto University·JournalCommunications Biology·TypeExperimental study·DateJun 2, 2026

USC researchers use AI to uncover genetic blueprint of the brain’s largest communication bridge

The study identified dozens of genetic regions that influence the size and thickness of the corpus callosum and its subregions. The research team created an AI-powered tool that finds and measures the corpus callosum in brain MRI scans automatically, allowing for unprecedented analysis of brain structure at scale and precision.

SourceKeck School of Medicine of USC·JournalNature Communications·TypeImaging analysis·DateNov 4, 2025

Follow the cellular road

Researchers have successfully visualized and tracked specific cells in deep brain tissue, including along the corpus callosum's nerve fibre highway. This advancement could potentially lead to better diagnostic tools for glioblastoma, a deadly brain cancer.

SourceEuropean Molecular Biology Laboratory·JournalNature Communications·DateSep 10, 2024

Ancient virus genome drives autism?

Research at Kobe University reveals that endogenous retrovirus activation increases a fetus's susceptibility to autism, leading to differences in brain structure and behavior. The study identifies BTBR/R mice as a more accurate model of autism, exhibiting autistic-like behaviors without reduced learning ability.

SourceKobe University·JournalMolecular Psychiatry·TypeExperimental study·DateMar 9, 2023

How playing the drums changes the brain

Researchers found that professional drummers have fewer but thicker fibres in the corpus callosum, a brain structure responsible for motor planning. This leads to more efficient brain organisation and better performance in drumming tasks. The study also revealed that drummers' brains are less active in motor tasks.

SourceRuhr-University Bochum·JournalBrain and Behavior·DateDec 9, 2019

Phantom limb sensation explained

A new study published in Scientific Reports found that brain areas responsible for movement and sensation alter their functional communication after a limb amputation. Researchers discovered that sensitive and motor areas of the brain exhibited abnormal patterns of communication among hemispheres, even in patients without phantom pain.

SourceD'Or Institute for Research and Education·JournalScientific Reports·DateFeb 21, 2019

Stanford researchers probe the complex nature of concussion

Researchers found that concussions occur when a deep area of the brain shakes rapidly and intensely, straining surrounding tissues. The study's findings suggest a complex relationship between head impacts and brain motion, highlighting the need for further research to improve diagnosis, treatment, and prevention of concussions.

SourceStanford University·JournalPhysical Review Letters·DateMar 30, 2018

Astroglia zip the 2 halves of the brain together

A study published in Cell Reports reveals that astroglial cells play a crucial role in forming the corpus callosum, a bridge-like structure connecting the two hemispheres of the brain. Without this cellular support, callosal agenesis occurs, affecting 1 in 4,000 people and leading to developmental disorders.

SourceCell Press·JournalCell Reports·DateOct 11, 2016

New insights into the male bias of autism

Research published in Molecular Autism found that male toddlers with autism have distinct brain structure changes compared to females, suggesting separate evaluation and early developmental markers. Additionally, studies suggest a 'female protective effect' through sex differences in genes and prenatal hormones.

SourceBMC (BioMed Central)·JournalMolecular Autism·DateMay 12, 2015

2 brain halves, 1 perception

Research reveals that specific fibre tracts in the corpus callosum are linked to individual differences in perceived visual motion. The connection affects how people perceive horizontal and vertical motion, with some individuals better at integrating information from both hemispheres.

SourceMax-Planck-Gesellschaft·JournalCurrent Biology·DateSep 1, 2011