Researchers at RIKEN discovered a way to prevent liver cancer spread by treating with a modified fucose sugar. The treatment disrupts biological pathways, blocking hepatoma cells from invading healthy liver cells and suppressing migration, but not proliferation.
Researchers identified R-LA induced cellular changes, inhibiting glucose production from non-carbohydrate sources. This study suggests a potential therapeutic approach for liver cancer treatment.
A US study found that liver transplantation significantly improves five-year survival rates for patients with hepatocellular carcinoma (HCC), from 25.3% in the late 1980s to 61.1% in the early 2000s. The study suggests that careful patient selection based on improved criteria may be a key factor in these improvements.