Peripheral Blood Mononuclear Cells
Articles tagged with Peripheral Blood Mononuclear Cells
Blood immune cell analysis tested in patients shows promise for early Parkinson’s detection
Researchers have developed a blood test that detects Parkinson's disease by analyzing the activity of immune cells. The study found 22 genes whose expression was altered in patients with Parkinson's, suggesting potential diagnostic markers and insights into the disease's mechanisms.
University of Cincinnati Cancer Center presents research at AACR 2025
Researchers from the University of Cincinnati Cancer Center presented abstracts highlighting contrasting effects of a protein on head and neck, breast, and lung cancers. The study found increased levels of IL-9 in patients with head and neck cancer correlated with decreased survival, while elevated IL-9 was associated with smaller tumo...
Revolutionary nanodrones enable targeted cancer treatment
Researchers have developed nanodrones that target and eliminate cancer cells by recruiting natural killer cells to tumor sites. The study offers a potential solution for intractable types of cancers, with promising results in suppressing tumor growth without causing side effects.
Innovative technology shows great promise against certain head and neck cancers
Researchers have developed a microfluidic squeezing technology that stimulates anti-tumor activity in a subtype of HPV16-positive head and neck, cervical, and anal cancers. The treatment uses peripheral blood mononuclear cells trained to recognize and attack cancer cells without genetic modifications.
Study explores effects of resistance training in older adults at the cellular level
A new study by researchers at Florida Atlantic University explored the effects of resistance training on older adults' cellular level. The study found that resistance training did not significantly affect inflammatory proteins or redox balance markers, but showed a significant reduction in a specific protein ratio. This may support the...
Study shows immune cells against COVID-19 stay high in number six months after vaccination
Researchers found that CD4+ T lymphocytes — immune system cells — produced by people who received COVID-19 vaccines persisted at high levels six months after vaccination, with a significant response against the delta variant. The study also showed that vaccine-elicited fighters recognize and help attack coronavirus delta variant.
Tumor microenvironment analyzed to increase effectiveness of preclinical trials
A Russian scientist has received funding to analyze the tumor microenvironment and develop new cancer therapies. The project aims to create targeted treatments with minimal side effects, building on gene and cell technologies.
Homogeneous BTK occupancy assay
The new assay enables simultaneous measurement of tirabrutinib bound and total BTK levels, reducing sample requirements. It uses full-length purified recombinant human BTK protein and PBMCs derived from healthy volunteers and patients with CLL, demonstrating its utility for pharmacodynamic assessments.
Night shift work and human health
Research suggests that night shift work can disrupt human circadian rhythms, leading to gene expression changes and immune system dysregulation. The study's findings highlight the potential risks of long-term night shift work on human health, particularly in relation to medical disorders such as diabetes and cancer.
Association found between length of biological marker and development of respiratory infection
Researchers found that shorter telomere lengths in certain cells are associated with an increased risk of developing upper respiratory infections. The study, published in JAMA, suggests a link between telomere shortening and immune system dysfunction in younger, healthy populations.
Researchers discover gut tissue to be a major reservoir harboring HIV
Researchers found that the human gut stores a significant amount of HIV, equivalent to nearly twice the amount in the bloodstream. The gut's role in harboring the virus was not fully understood until now.