Articles tagged with Rectum
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A recent NUS Medicine study found that a molecule called DUSP6 plays a major role in helping colorectal cancer grow, with higher levels linked to poorer prognosis and decreased survival. Researchers suggest blocking DUSP6 could lead to new therapies for CRC treatment.
The updated ASTRO guideline recommends personalized treatment approaches for patients with locally advanced rectal cancer, including non-surgical alternatives and intensified treatment regimens. The guideline aims to improve outcomes while preserving quality of life.
A new study published in Annals of Oncology found that long-course radiotherapy is safer and more effective than short-course radiotherapy for preserving organs in rectal cancer patients. The treatment was shown to prevent regrowth of the primary tumour, but had similar overall survival rates.
A new treatment approach has been confirmed effective in a major study, showing that locally advanced rectal cancer patients can experience complete tumour disappearance without needing surgery. This method reduces the risk of recurrence and preserves normal bowel function, offering a promising alternative to traditional treatments.
A study published in the Journal of the American College of Surgeons found that hospitals accredited by the National Accreditation Program for Rectal Cancer (NAPRC) demonstrate significantly better outcomes for patients undergoing rectal cancer surgery. These institutions show lower rates of mortality, complications, and morbidity comp...
A study of 34,500 patients found racial and ethnic disparities in locally advanced rectal cancer treatment outcomes may be influenced by unidentified biological or social factors. Non-Hispanic Black patients were more likely to experience poorer outcomes.
Researchers propose a new method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing, which can provide valuable information on CRC progression and response to therapy. This analysis may also reduce costs and time required for staging CRC patients.
Researchers have shed light on the molecular mechanisms allowing beetles to absorb water rectally, a property enabling them to survive in extremely dry environments. This knowledge could be used to develop more targeted and eco-friendly methods to combat beetle species that destroy food production.
The TTUHSC team will provide no-cost colorectal cancer screening and colonoscopies to underinsured and uninsured people living in South Plains region counties. The FIT-STOP program aims to find signs of early-stage colorectal cancer to prevent treatment needs, leveraging existing relationships with partners.
New guidelines from the American Society of Colon and Rectal Surgeons provide updated treatment recommendations for anorectal abscess, anal fistula, and rectovaginal fistula. The guidelines emphasize the importance of both surgical approaches and medication options in managing these conditions.
Researchers at Case Western Reserve University are developing an AI tool to analyze medical images and determine which rectal cancer patients require surgery. By using radiomics and machine learning techniques, the team hopes to identify patients who can avoid invasive surgery and opt for chemotherapy or radiation therapy instead.
Scientists successfully deliver oxygen through the lining of the intestine, a process called enteral ventilation or EVA, to alleviate respiratory failure. The method shows promise for reducing negative effects of oxygen deprivation and has potential as a less invasive alternative to traditional ventilators.
Researchers have identified a non-invasive and targeted treatment to correct nerve damage and address the pervasive problem of fecal incontinence. Magnetic stimulation of nerves regulating muscles in the anus and rectum improves function and reduces episodes of fecal incontinence in patients.
The updated guidelines reflect a shift towards outpatient care and non-emergency surgery for left-sided colonic diverticulitis. Key findings include the preference for minimal colectomy approaches when expertise is available, and an increased focus on evidence-based recommendations.
A study found that home-based biofeedback therapy is about 70 percent effective in helping patients learn to coordinate and relax bowel muscles to relieve dyssynergic defecation. The therapy involves using a reusable sensor probe connected to a handheld pressure monitor to provide visual feedback on muscle contractions.
Dysynergic defecation is a condition where the brain and gut communicate improperly, leading to constipation and abdominal pain. Researchers have developed a biofeedback system that helps patients relearn normal behavior and restore communication between the brain and gut, showing an 85% success rate.
A study found that 30 children with bedwetting had excess stool in their rectums, despite normal bowel habits. After treatment with laxative therapy, 83% of the children were cured of bedwetting within three months.
Researchers found that tissue spacers significantly reduced the rectal dose administered to patients receiving radiation therapy for prostate cancer. This led to minimal damage to the rectum, enabling radiation oncologists to increase treatment doses without concern.
A single sigmoidoscopy examination between ages 55 and 64 significantly reduced colorectal cancer mortality by 43% and incidence by one-third in those screened. The study found a lasting protective effect of screening, with 59% of cases detected during screening and only a few post-screening detections.
Researchers found that technically efficient screening and diagnostic colonoscopy requires experience with 150 cases or more. The trainees' skill at cecal intubation improved significantly after performing 150 procedures.