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Fungi utilize ancient antimicrobial proteins to attack hosts and their microbiomes

Researchers discovered that fungal effector proteins evolved from ancient antimicrobial proteins to weaken host immune systems and manipulate the surrounding microbiome. These findings provide new insights into how fungi attack both hosts and beneficial microorganisms, with potential applications in agriculture and medicine.

SourceUniversity of Cologne·JournalScience Advances·TypeExperimental study·DateMay 5, 2026

Novel wheat hybrids increase resistance to major fungal disease by up to 70%

Researchers have identified a novel genetic locus in the common agricultural weed Elymus repens that provides significant resistance to Fusarium Head Blight, a destructive fungal disease threatening global food security. The novel Fhb.Er-1StL locus has been successfully transferred into wheat, reducing diseased plant spikelets by up to...

SourceSociety for Experimental Biology·JournalJournal of Experimental Botany·TypeExperimental study·DateMay 4, 2026

A pathogen-induced translational shift enhances plant disease resistance without obvious fitness costs

A team of scientists has developed a technical system for regulating plant disease resistance without obvious fitness costs. They achieved this by identifying and utilizing in-frame AUGs in functional genes, including PI4KIII β1, to specifically regulate resistance gene expression through protein translation reprogramming.

Novel structural insights into Phytophthora effectors challenge long-held assumptions in plant pathology

Researchers at FABI define a conserved subset of Phytophthora RxLR effectors with short linear motifs embedded within folded WY domain cores. This arrangement preserves domain integrity while enabling potential interactions with host immune components, reframing pathogen strategies and challenging SLiM dogma.

SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·DateFeb 24, 2026

Biologists and engineers follow goopy clues to plant-wilting bacteria

Researchers found that Ralstonia's unique exo polysaccharide 1 (EPS-1) film allows the bacteria to spread rapidly through plant xylem vessels, causing rapid wilting. The team used precise measurements of the viscoelastic properties of EPS-1 to understand its role in making Ralstonia a devastating plant killer.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJan 23, 2026

How wheat protects itself from fungi

Researchers discovered a previously unknown interplay between wheat's resistance genes and fungal disease factors. The study found that powdery mildew fungus overcomes resistance by modifying recognized effectors, but a new approach could slow down its development by combining targeted resistance genes.

SourceUniversity of Zurich·JournalNature Plants·TypeExperimental study·DateJan 12, 2026

Fungal allies arm plant roots against disease by rewriting the rules of infection

Researchers discovered that beneficial fungi enhance plant resistance to disease by remodelling the plant cell membrane at pathogen infection sites. This transformation coincides with a significant reduction in pathogen colonisation and offers critical new insights into how plants coordinate defences in complex natural environments.

SourceUniversity of Cambridge·JournalCell Reports·TypeExperimental study·DateDec 11, 2025

Grains of truth: New focus issue explores how pathogens and pests of cereal crops undermine global food security

The latest focus issue of Molecular Plant-Microbe Interactions explores the molecular, cellular, and genomic details of cereal crop diseases, highlighting key research on plant-pathogen interactions. Groundbreaking work has advanced the field, offering new insights into disease resistance and management strategies.

SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·DateMay 7, 2025

Protecting crops: Researchers open up new avenue to combat a widespread plant virus

Researchers at Martin-Luther-Universität Halle-Wittenberg have developed a new avenue to combat the Cucumber mosaic virus by directing the plant's natural defences. The RNA-based active agents have shown high efficacy in laboratory experiments, protecting 80-100% of treated plants from infection.

SourceMartin-Luther-Universität Halle-Wittenberg·JournalNucleic Acids Research·TypeExperimental study·DateMar 18, 2025

Lowering bioenergetic age may help fend off Alzheimer’s

Researchers found that individuals with lower acylcarnitine levels declined more slowly and showed fewer cognitive decline symptoms compared to those with high acylcarnitine levels. Healthy lifestyle interventions, such as a plant-based diet and exercise, may help lower bioenergetic age and potentially delay or prevent Alzheimer’s onset.

SourceWeill Cornell Medicine·JournalNature Communications·DateMar 13, 2025

Uprooting Cassava Disease: scientists identify causes of two devastating diseases

Researchers have identified the pathogens and diagnostic tests for the two diseases, revolutionizing cassava disease management in Latin America, the Caribbean, and Southeast Asia. The study, published in peer-reviewed journals, marks a significant milestone in fighting the spread of these devastating diseases.

Advances and applications in single-cell and spatial genomics

This review highlights the transformative capabilities of single-cell and spatial genomics, providing critical insights into disease mechanisms and developing innovative therapies. The technologies enable comprehensive cell atlases, tracing the evolution of sequencing methods and incorporating multi-omics approaches, which significantl...

SourceScience China Press·JournalScience China Life Sciences·DateJan 12, 2025