Articles tagged with Sphingolipid Signaling
Researchers have discovered the crucial role of lipids in the organisation of the bacterial genome, revealing a new avenue for medical research. The study reveals that lipids play a central regulator role in controlling access to the genes, offering a new strategic target for medicine
Researchers from NUS Medicine and St. Jude Children's Research Hospital have discovered how blood cells release S1P, a key signalling lipid, into the bloodstream. S1P plays a crucial role in keeping blood vessels healthy and supporting normal cell function. The study used cryo-electron microscopy and computer simulations to capture a d...
A team of scientists discovered that ceramides accumulate in muscles during aging, leading to a decline in muscle function. Treating old mice with ceramide blockers prevented age-related loss of muscle mass and improved muscle strength.
A new study suggests that exercise training is crucial for individuals with diet-resistant obesity, improving skeletal muscle metabolism and enhancing weight loss capacity. The research challenges the one-size-fits-all approach to treating obesity and has the potential to help reshape the science of weight-loss programs.
Researchers at EPFL's School of Life Sciences discovered that blocking sphingolipid synthesis can reverse the symptoms of Duchenne muscular dystrophy, including loss of muscle function and inflammation. This study identifies sphingolipid inhibition as a potential treatment for muscular dystrophies.
Researchers discovered a potential way to prevent mosquito-borne diseases like Zika and dengue by targeting the sphingolipid pathway in the midgut. This approach could stall viral replication and prevent transmission to humans.
The American Society for Biochemistry and Molecular Biology (ASBMB) has selected eight scientists for its annual awards competition, recognizing their contributions to science. The award winners include David Davies, John Kuriyan, Sarah Spiegel, Susan Lindquist, Douglas Rees, Phillip Zamore, Sandra Schmid, and Rochelle Schwartz-Bloom.