Articles tagged with Alkyl Groups
A team of UNLV researchers has engineered a new class of cannabidiol (CBD)-like medicines that show powerful seizure-reducing effects. The caraway-seed derived therapies offer a safer and more effective treatment for childhood seizure disorders than existing frontline therapies.
Researchers at Chiba University developed a method for selectively attaching an alkyl group to the C5 position of indole using a copper-based catalyst, producing yields of up to 91%. This approach could enable more affordable and scalable modification of indoles, crucial for drug development.
Researchers achieved a new method for synthesizing α-substituted carbonyl compounds using a palladium-catalyzed anti-Michael addition reaction. The method produces high-yield products and can be applied to various nucleophiles, including indoles and aromatic compounds.
Researchers developed a gel electret capable of stably retaining electrostatic charge and combining it with flexible electrodes to create a vibration sensor. The device achieves an 83% increase in output voltage compared to previous alkyl–π liquid electret-based sensors, enabling potential use as wearable healthcare sensors.
A team from The Institute of Industrial Science at The University of Tokyo has developed a new platform that uses organorhodium(III) phthalocyanine complexes to achieve the combination of traits necessary for photodynamic therapy. The new system shows toxicity to HeLa cells, indicating its potential as a cancer treatment.
New phenothiazine derivatives containing phenyl groups show high potential for use as photochemical agents in surgical operations and cancer treatment. The compounds' stability was ensured through the formation of binary associates, providing greater absorption in near-infrared spectrum.
Researchers at Osaka University have developed a method to form bonds between two butadiene molecules, an alkyl group, and benzene rings using a cheap nickel catalyst. This technique enables the synthesis of high-value terminal olefins from cheap butadiene, which can be used in various industrial applications.
Direct C–H transformations aim to perform synthetic chemistry in a greener and more atom-economical way. Several generations of chemists collectively made significant progress in inert aliphatic C–H bond functionalization.