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Technique for tracking resistant cancer cells could lead to new treatments for relapsing breast cancer patients

Researchers from the University of Cambridge have identified a method to track and kill resistant cancer cells in mice. By tagging different types of breast cancer cells with unique genetic barcodes, they were able to identify which cells are evading chemotherapy and target them specifically with a new treatment approach.

SourceUniversity of Cambridge·JournaleLife·TypeExperimental study·DateDec 20, 2022

Scientists halt breast cancer spread

Researchers found that restricting asparagine production in mice greatly reduced breast cancer's ability to spread, suggesting a potential new treatment approach. The study also suggests that dietary changes may help stop cancer from spreading and improve outcomes for patients.

SourceCancer Research UK·JournalNature·DateFeb 7, 2018

Leukemic cells find safe haven in bone marrow

Research at St. Jude Children's Research Hospital shows that leukemic cells receive a protective niche from bone marrow mesenchymal cells, which release the amino acid asparagine to help them survive treatment with asparaginase. This finding suggests new strategies for enhancing anti-leukemic drugs and reducing leukemia recurrence rates.

SourceSt. Jude Children's Research Hospital·JournalJournal of Clinical Investigation·DateMar 22, 2007

How acrylamide might be formed in starch-rich foods

Cornell University professor Bruce Ganem proposes an alternative chemical pathway for acrylamide formation in fried or baked foods. He suggests that enzymatic decarboxylation of asparagine is the key step in this process, leading to the loss of carbon dioxide and the formation of acrylamide.

SourceCornell University·JournalChemical & Engineering News·DateDec 19, 2002