Articles tagged with Dendrimers
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers from Japan and Germany have created an eco-friendly light-emitting electrochemical cell using dendrimers combined with biomass-derived cellulose acetate as the electrolyte and a graphene electrode. The device has a long lifespan of over 1000 hours and is environmentally friendly.
Researchers develop a method to synthesize bare aromatic polymers using dendrimer support, enabling high solubility and transfer to other materials. This innovation opens up new possibilities for creating hybrid materials with unique properties.
A small clinical trial found that OP-101 substantially reduced the risk of death and need for a ventilator in severely ill adults hospitalized with COVID-19. The treatment also showed significant benefits in decreasing biomarkers of inflammation and brain injury, suggesting potential for treating long COVID-related symptoms.
Researchers develop a novel nanoplatform that can deliver drugs directly to T cells, which play a crucial role in immune reactions. The platform uses pH-sensitive dendrimers with phenylalanine and has shown promising results for cancer immunotherapy.
Researchers have discovered that dendrimer tentacles can avoid detection by the complement system, part of our immune system. This could lead to developing a new system for delivering drugs into the body without triggering an immune response.
Researchers have developed a novel method to synthesize sub-nanoparticles (SNPs) with controlled composition and size, enabling the discovery of unique properties. The team found unusual electronic states and oxygen content in SNPs with an indium-to-tin ratio of 3:4, leading to different optical properties.
Researchers at the University of Tsukuba have developed a new crystalline material that reversibly changes color from yellow to red when absorbing water, indicating the presence of water. This work could lead to the creation of highly sensitive vapochromic sensors that can detect gases or water vapor without external power.
Researchers from the University of Tsukuba have synthesized branched polymer crystals that can be used as tiny laser sources, overcoming dendrimers' fragility and poor crystallinity. The new material exhibits lasing properties and shows promising potential for applications in displays and micro-optical circuits.
Researchers created DNA-based dendrimers that form rigid nanocages with controlled voids, preventing back-folding and maintaining structure even in high-salt concentrations. These nanocages show promise as functional carriers for medicine and material engineering applications.
Researchers at Tokyo Institute of Technology have developed a method to synthesize multimetallic clusters with precise control of size and composition, opening up new possibilities for advanced functional materials. The team successfully formed clusters composed of up to six metal elements, including platinum.
Researchers at Lomonosov Moscow State University have developed protein-dendrimer films with self-assembly properties, retaining enzyme activity and function. The films show promise as biosensor materials and bioactive dressings for medical applications.
Scientists at University of Tsukuba create effective fluorescent sensor for detecting solvent vapor, utilizing a branched molecule called a dendrimer. The sensor can distinguish between various solvents through changes in emission color and intensity.
Scientists create arrays of nanocontainers with tailored interaction strengths by mimicking electron valency in atoms. The approach enables plasmonic sensors and electrocatalysts, showcasing a new aspect of atom mimicry for nanotechnology applications.
Researchers at EPFL have developed a technology that accelerates scarring and prevents bacterial growth, aiming to reduce the death rate among victims of serious burns. The new bandage combines biological bandages with dendrimers to destroy microbes and prevent infections.
Researchers used dendrimers to track and isolate proteins involved in cell entry pathways, identifying 809 proteins. This technology could lead to more targeted drug delivery and improve our understanding of viruses.
University of Pennsylvania researchers have developed a novel method to create stable, onion-like vesicles using dendrimers. By controlling the concentration of dendrimers, they can produce vesicles with multiple layers, allowing for sequential release of drugs and potential clinical applications.
Researchers at Berkeley Lab develop a new technique to create sustainable heterogenized homogeneous nanocatalysts with high reactivity and selectivity. This breakthrough combines the best properties of both heterogeneous and homogeneous catalysts, enabling control over product distribution in industrial chemistry processes.
Researchers developed nano-devices that successfully crossed the blood-brain barrier and delivered a drug to tame brain-damaging inflammation in rabbits with cerebral palsy. The treatment improved motor skills and reduced neuro-inflammation, holding promise for treating a range of neurologic disorders.
Researchers have developed an intracellular, sustained-release drug delivery system using nanoparticles called dendrimers, targeting neuroinflammation in the retina. The treatment protects vision by preventing injury to photoreceptors and reduces neuroinflammation, providing potential relief for millions of patients worldwide.
Researchers at Wayne State University, Mayo Clinic and Johns Hopkins have developed a targeted drug delivery system using nanoparticles called dendrimers. This system reduced neuroinflammation in the retina and protected vision by preventing injury to photoreceptors.
Researchers have created a highly sensitive surface that enables multivalent binding, allowing for the efficient capture of circulating tumor cells from the blood. The combination of nanotechnology and biomimicry demonstrates great potential for detecting rare tumor cells.
A theoretical model compares the transport characteristics of straight- and branched-chain polymers in channels, shedding light on how deformability affects their movement. The findings could aid in developing carrier molecules for targeted drug delivery.
Researchers have developed synthetic biomaterials that mimic cellular membranes, showing promise in targeted delivery of cancer drugs and gene therapy. The new materials, called dendrimersomes, offer stability, mechanical strength, and tunable properties.
Researchers have developed PEGylated Polylysine dendrimers as a novel mechanism of drug delivery, targeting either the lymphatic system or bloodstream. The technology offers improved treatment options for diseases such as cancer, HIV, and lymphatic conditions worldwide.
Scientists at the University of California, Berkeley and Los Alamos National Laboratory have developed a comprehensive numerical study of gene therapy. The research sheds light on the key factors that determine the success of dendrimers as gene delivery vehicles, including the charges of the dendrimers and their target cell membranes.
Researchers have developed multifunctional nanoparticles that target and image cancer cells by exploiting overexpression of folic acid receptors. These dendrimer-based systems can accumulate in diseased cells and retain bright fluorescence, allowing for easy visualization via confocal microscopy.
Dendrimers have shown promise for precisely delivering drugs to their targets inside the body, but high concentrations can be toxic. Researchers discovered that engineering dendrimers in particular ways can prevent this damage and make them better at what they do.
Researchers have developed a method to assemble nanoparticles using DNA molecules, enabling targeted delivery of drugs and contrast agents to cancer cells. The approach uses dendrimers, star-like synthetic polymers that can carry multiple molecules, and allows for rapid synthesis and self-assembly of nanoparticle complexes.
The U-M group uses lab-made dendrimers as the backbone of their delivery system, which can attach targeting agents to recognize cancer cells and deliver lethal doses while leaving normal cells unharmed. Early results show that nanoparticle drugs effectively treat cancer with fewer side effects than conventional chemotherapy.
Researchers at the University of Illinois have developed a new molecular imprinting process to create artificial antibodies. The technique involves imprinting a single molecule within a highly branched polymer called a dendrimer, allowing for specific binding and rejection of target molecules. This breakthrough has potential applicatio...
Researchers successfully tracked stem cells implanted into a living rat using a magnetic resonance imaging technique, marking an important breakthrough. The iron-laden cells create a magnetic black hole easily spotted by MRI, allowing scientists to monitor the cells' behavior and movement without tissue removal.
Researchers at Ohio State University have successfully created protein-like molecules using dendrimers, which can perform tasks such as delivering medicine to tumors and acting as catalysts for chemical reactions. The molecules are designed to open and close on cue, allowing them to respond to stimuli like light.
Jean M.J. Frechet, a renowned Berkeley chemist, has been honored with the 2001 Arthur C. Cope Scholar Award for his groundbreaking research on dendrimers, complex organic compounds with various applications, including drug delivery to tumors and light-harvesting antennae.
Researchers at the University of Rochester have determined an improved pattern for artificial light-harvesting molecules, finding a point of diminishing returns for larger dendrimers. This breakthrough could lead to more efficient chemical reactions and applications in fields like medicine and renewable energy.
Researchers develop dendrimer supermolecules that funnel light energy through a tree-like structure, directing it to a central point. The nanostar molecule can convert ultraviolet light into visible light with up to 99% efficiency, making it suitable for various applications such as solar energy harvesting and optical sensors.