Scientists reveal the secret of the enzyme without an arginine fingers, which can effectively transmit cellular signals
Researchers found that a protein activator clamps down the active center of GTPase Ran, allowing efficient hydrolysis. This discovery may lead to the development of cancer drugs blocking this process.
SourceFederal Research Centre «Fundamentals of Biotechnology» of the Russian Academy of Science·JournalACS Catalysis·DateJul 28, 2021